安藤 創一
| 共通教育部（研究科） | 准教授 |
| 共通教育部（学域） | 准教授 |
| 脳・医工学研究センター | 准教授 |
| 機械知能システム学専攻 | 准教授 |
| Ⅱ類（融合系） | 准教授 |
研究者情報
研究活動情報
論文
- Human dopaminergic system in the exercise-cognition link
Meijun Hou; Fabian Herold; Zhihao Zhang; Soichi Ando; Boris Cheval; Sebastian Ludyga; Kirk I. Erickson; Charles H. Hillman; Qian Yu; Teresa Liu-Ambrose; Jin Kuang; Arthur F. Kramer; Yanxia Chen; Joseph T. Costello; Chong Chen; Olivier Dupuy; Dominika M. Pindus; Terry McMorris; Lars Stiernman; Liye Zou
Trends in Molecular Medicine, Elsevier BV, 30巻, 8号, 掲載ページ 708-712, 出版日 2024年08月, 査読付
研究論文（学術雑誌） - Effects of voluntary exercise and electrical muscle stimulation on reaction time in the Go/No-Go task
Mizuki Sudo; Daisuke Kitajima; Yoko Takagi; Kodai Mochizuki; Mami Fujibayashi; Joseph T. Costello; Soichi Ando
European Journal of Applied Physiology, Springer Science and Business Media LLC, 出版日 2024年07月23日, 査読付
研究論文（学術雑誌） - Beyond FITT
Fabian Herold; Liye Zou; Paula Theobald; Patrick Manser; Ryan S. Falck; Qian Yu; Teresa Liu-Ambrose; Charles H. Hillman; Arthur K. Kramer; Kirk I. Erickson; Boris Cheval; Yanixa Chen; Matthew Heath; Zhihao Zhang; Toru Ishihara; Keita Kamijo; Soichi Ando; Yanping Gao; Joseph P. Costello; Meijun Hou; Mats Hallgren; Zhuhui Chen; David Moreau; Vahid Farrahi; David A. Raichlen; Emmanuel Stamatakis; Michael J. Wheeler; Neville Owen; Sebastian Ludyga; Henning Budde; Thomas Gronwald
Society for Transparency, Openness, and Replication in Kinesiology, 出版日 2024年05月21日
研究論文（学術雑誌） - Combined effects of electrical muscle stimulation and cycling exercise on cognitive performance
Soichi Ando; Yuka Ishioka; Sari Kambayashi; Kosuke Kano; Mami Fujibayashi; Joseph T. Costello; Mizuki Sudo
Frontiers in Physiology, Frontiers Media SA, 15巻, 出版日 2024年05月17日, 査読付, The purpose of this study was to investigate whether a combination of electrical muscle stimulation (EMS) and cycling exercise is beneficial for improving cognitive performance. Eighteen participants (7 females and 11 males) performed a Go/No-Go task before and 2 min after i) cycling exercise (EX), ii) a combination of EMS and cycling (EMS + EX) and iii) a control (rest) intervention in a randomized controlled crossover design. In the EX intervention, the participants cycled an ergometer for 20 min with their heart rate maintained at ∼120 beats·min-1. In the EMS + EX intervention, the participants cycled an ergometer simultaneously with EMS for 20 min, with heart rate maintained at ∼120 beats·min-1. In the Control intervention, the participants remained at rest while seated on the ergometer. Cognitive performance was assessed by reaction time (RT) and accuracy. There was a significant interaction between intervention and time (p = 0.007). RT was reduced in the EX intervention (p = 0.054, matched rank biserial correlation coefficient = 0.520). In the EMS + EX intervention, RT was not altered (p = 0.243, Cohen’s d = 0.285) despite no differences in heart rate between the EX and EMS + EX interventions (p = 0.551). RT was increased in the Control intervention (p = 0.038, Cohen’s d = −0.529). These results indicate that combining EMS and cycling does not alter cognitive performance despite elevated heart rate, equivalent to a moderate intensity. The present findings suggest that brain activity during EMS with cycling exercise may be insufficient to improve cognitive performance when compared to exercise alone.
研究論文（学術雑誌） - The neuromodulatory role of dopamine in improved reaction time by acute cardiovascular exercise
Soichi Ando; Toshihiko Fujimoto; Mizuki Sudo; Shoichi Watanuki; Kotaro Hiraoka; Kazuko Takeda; Yoko Takagi; Daisuke Kitajima; Kodai Mochizuki; Koki Matsuura; Yuki Katagiri; Fairuz Mohd Nasir; Yuchen Lin; Mami Fujibayashi; Joseph T. Costello; Terry McMorris; Yoichi Ishikawa; Yoshihito Funaki; Shozo Furumoto; Hiroshi Watabe; Manabu Tashiro
The Journal of Physiology, 出版日 2024年02月, 査読付
研究論文（学術雑誌） - Eight-week neuromuscular electrical stimulation training produces muscle strength gains and hypertrophy, and partial muscle quality improvement in the knee extensors
Ryota Akagi; Yusuke Miyokawa; Daigo Shiozaki; Yoshinari Yajima; Koki Yamada; Kosuke Kano; Yuto Hashimoto; Takanobu Okamoto; Soichi Ando
Journal of Sports Sciences, 出版日 2023年12月17日, 査読付
研究論文（学術雑誌） - Cognitive Function among Young Women’s Football Players in the Summer Heat
Soichi Ando; Nana Ogoh; Shotaro Saito; Hironori Watanabe; Maki Ohsuga; Tetsuya Hasegawa; Shigehiko Ogoh
Translational Sports Medicine, Hindawi Limited, 2023巻, 掲載ページ 1-5, 出版日 2023年11月02日, 査読付, Recently, there has been a growing focus on studies related to women’s football. However, the cognitive function of female football players has not been extensively characterized. Thus, we explored how the cognitive function of female football players was altered during a series of matches in summer and examined day-to-day variations in cognitive function with regard to dehydration status. Resting cognitive function was assessed from 17 young women football players during the Japan Club Youth Women’s football tournament, which spanned eight consecutive days. Cognitive function initially improved, with this improvement sustained throughout the tournament. It is worth noting that ten participants experienced symptoms of dehydration at least once during the tournament; however, these symptoms were not found to be linked to impaired cognitive function, suggesting that resting cognitive function remains unaffected during summer matches, even in the presence of dehydration symptoms.
研究論文（学術雑誌） - Acute hypoxia impairs posterior cerebral bioenergetics and memory in man
Ando S; Tsukamoto H; Stacey BS; Washio T; Owens TS; Calverley TA; Fall L; Marley CJ; Iannetelli A; Hashimoto T; Ogoh S; Bailey DM
Exp Physiol, 出版日 2023年10月, 査読付, 国際誌, Hypoxia has the potential to impair cognitive function; however, it is still uncertain which cognitive domains are adversely affected. We examined the effects of acute hypoxia (∼7 h) on central executive (Go/No-Go) and non-executive (memory) tasks and the extent to which impairment was potentially related to regional cerebral blood flow and oxygen delivery (CDO2 ). Twelve male participants performed cognitive tasks following 0, 2, 4 and 6 h of passive exposure to both normoxia and hypoxia (12% O2 ), in a randomized block cross-over single-blinded design. Middle cerebral artery (MCA) and posterior cerebral artery (PCA) blood velocities and corresponding CDO2 were determined using bilateral transcranial Doppler ultrasound. In hypoxia, MCA DO2 was reduced during the Go/No-Go task (P = 0.010 vs. normoxia, main effect), and PCA DO2 was attenuated during memorization (P = 0.005 vs. normoxia) and recall components (P = 0.002 vs. normoxia) in the memory task. The accuracy of the memory task was also impaired in hypoxia (P = 0.049 vs. normoxia). In contrast, hypoxia failed to alter reaction time (P = 0.19 vs. normoxia) or accuracy (P = 0.20 vs. normoxia) during the Go/No-Go task, indicating that selective attention and response inhibition were preserved. Hypoxia did not affect cerebral blood flow or corresponding CDO2 responses to cognitive activity (P > 0.05 vs. normoxia). Collectively, these findings highlight the differential sensitivity of cognitive domains, with memory being selectively vulnerable in hypoxia. NEW FINDINGS: What is the central question of this study? We sought to examine the effects of acute hypoxia on central executive (selective attention and response inhibition) and non-executive (memory) performance and the extent to which impairments are potentially related to reductions in regional cerebral blood flow and oxygen delivery. What is the main finding and its importance? Memory was impaired in acute hypoxia, and this was accompanied by a selective reduction in posterior cerebral artery oxygen delivery. In contrast, selective attention and response inhibition remained well preserved. These findings suggest that memory is selectively vulnerable to hypoxia.
研究論文（学術雑誌）, 英語 - The effects of environmental enrichment on voluntary physical activity and muscle mass gain in growing rats
Mizuki Sudo; Yutaka Kano; Soichi Ando
Frontiers in Physiology, Frontiers Media SA, 14巻, 出版日 2023年09月28日, 査読付, Introduction: Environmental enrichment (EE) for rodents involves housing conditions that facilitate enhanced sensory, cognitive, and motor stimulation relative to standard housing conditions. A recent study suggested that EE induces muscle hypertrophy. However, it remains unclear whether muscle hypertrophy in EE is associated with voluntary physical activity, and the characteristics of muscle adaptation to EE remain unclarified. Therefore, this study investigated whether muscle adaptation to EE is associated with voluntary physical activity, and assessed the changes in the muscle fiber-type distribution and fiber-type-specific cross-sectional area in response to EE.
Methods: Wistar rats (6 weeks of age) were randomly assigned to either the standard environment group (n = 10) or the EE group (n = 10). The voluntary physical activity of rats housed in EE conditions was measured using a recently developed three-axis accelerometer. After exposure to the standard or enriched environment for 30 days, the tibialis anterior, extensor digitorum longus, soleus, plantaris, and gastrocnemius muscles were removed and weighed. Immunohistochemistry analysis was performed on the surface (anterior) and deep (posterior) areas of the tibialis anterior and soleus muscles.
Results and discussion: The EE group showed increased voluntary physical activity during the dark period compared with the standard environment group (p = 0.005). EE induced muscle mass gain in the soleus muscle (p = 0.002) and increased the slow-twitch muscle fiber cross-sectional area of the soleus muscle (p = 0.025). EE also increased the distribution of high-oxidative type IIa fibers of the surface area (p = 0.001) and type I fibers of the deep area (p = 0.037) of the tibialis anterior muscle. These findings suggest that EE is an effective approach to induce slow-twitch muscle fiber hypertrophy through increased daily voluntary physical activity.
研究論文（学術雑誌） - Look into my eyes: What can eye-based measures tell us about the relationship between physical activity and cognitive performance?
Liye Zou; Fabian Herold; Sebastian Ludyga; Keita Kamijo; Notger G Müller; Matthew B Pontifex; Matthew Heath; Ryuta Kuwamizu; Hideaki Soya; Charles H Hillman; Soichi Ando; Brandon L Alderman; Boris Cheval; Arthur F Kramer
Journal of sport and health science, 出版日 2023年05月04日, 査読付, 国際誌, BACKGROUND: There is a growing interest to understand the neurobiological mechanisms that drive the positive associations of physical activity and fitness with measures of cognitive performance. To better understand those mechanisms, several studies have employed eye-based measures (e.g., eye movement measures such as saccades, pupillary measures such as pupil dilation, and vascular measures such as retinal vessel diameter) deemed to be proxies for specific neurobiological mechanisms. However, there is currently no systematic review providing a comprehensive overview of these studies in the field of exercise-cognition science. Thus, this review aims to address that gap in the literature. METHODS: To identify eligible studies, we searched 5 electronic databases on October 23rd 2022. Two researchers independently extracted data and assessed the risk of bias using a modified version of the Tool for the assEssment of Study qualiTy and reporting in EXercise (TESTEX scale, for interventional studies) and the critical appraisal tool from the Joanna Briggs Institute (for cross-sectional studies). RESULTS: Our systematic review (n = 35 studies) offers the following main findings: (a) there is insufficient evidence available to draw solid conclusions concerning gaze-fixation-based measures, (b) the evidence that pupillometric measures, which are a proxy for the noradrenergic system, can explain the positive effect of acute exercise and cardiorespiratory fitness on cognitive performance is mixed, (c) physical training- or fitness-related changes of the cerebrovascular system (operationalized via changes in retinal vasculature) are, in general, positively associated with cognitive performance improvements, (d) acute and chronic physical exercises show a positive effect based on an oculomotor-based measure of executive function (operationalized via antisaccade tasks), and (e) the positive association between cardiorespiratory fitness and cognitive performance is partly mediated by the dopaminergic system (operationalized via spontaneous eye-blink rate). CONCLUSION: This systematic review offers confirmation that eye-based measures can provide valuable insight into the neurobiological mechanisms that may drive positive associations between physical activity and fitness and measures of cognitive performance. However, due to the limited number of studies utilizing specific methods for obtaining eye-based measures (e.g., pupillometry, retinal vessel analysis, spontaneous eye blink rate) or investigating a possible dose-response relationship, further research is necessary before more nuanced conclusions can be drawn. Given that eye-based measures are economical and non-invasive, we hope this review will foster the future application of eye-based measures in the field of exercise-cognition science.
研究論文（学術雑誌）, 英語 - The effects of manipulating the visual environment on thermal perception: A structured narrative review
Harry S. Mayes; Martina Navarro; Liam P. Satchell; Michael J. Tipton; Soichi Ando; Joseph T. Costello
Journal of Thermal Biology, Elsevier BV, 112巻, 掲載ページ 103488-103488, 出版日 2023年02月, 査読付
研究論文（学術雑誌） - Effects of Three-Dimension Movie Visual Fatigue on Cognitive Performance and Brain Activity.
Akagi R; Sato H; Hirayama T; Hirata K; Kokubu M; Ando S
Front Hum Neurosci, 16巻, 974406号, 掲載ページ 974406-974406, 出版日 2022年10月, 査読付, 国際誌, To further develop three-dimensional (3D) applications, it is important to elucidate the negative effects of 3D applications on the human body and mind. Thus, this study investigated differences in the effects of visual fatigue on cognition and brain activity using visual and auditory tasks induced by watching a 1-h movie in two dimensions (2D) and 3D. Eighteen young men participated in this study. Two conditions were randomly performed for each participant on different days, namely, watching the 1-h movie on television in 2D (control condition) and 3D (3D condition). Before and after watching the 1-h movie on television, critical flicker fusion frequency (CFF: an index of visual fatigue), and response accuracy and reaction time for the cognitive tasks were determined. Brain activity during the cognitive tasks was evaluated using a multi-channel near-infrared spectroscopy system. In contrast to the control condition, the decreased CFF, and the lengthened reaction time and the decreased activity around the right primary somatosensory cortex during Go/NoGo blocks in the visual task at post-viewing in the 3D condition were significant, with significant repeated measures correlations among them. Meanwhile, in the auditory task, the changes in cognitive performance and brain activity during the Go/NoGo blocks were not significant in the 3D condition. These results suggest that the failure or delay in the transmission of visual information to the primary somatosensory cortex due to visual fatigue induced by watching a 3D movie reduced the brain activity around the primary somatosensory cortex, resulting in poor cognitive performance for the visual task. This suggests that performing tasks that require visual information, such as running in the dark or driving a car, immediately after using a 3D application, may create unexpected risks in our lives. Thus, the findings of this study will help outlining precautions for the use of 3D applications.
研究論文（学術雑誌）, 英語 - The effects of acute high intensity aerobic exercise on cognitive performance: a structured narrative review.
Sudo M; Costello JT; McMorris T; Ando S
Front Behav Neurosci, 16巻, 957677号, 掲載ページ 957677-957677, 出版日 2022年09月, 査読付, 国際誌, It is well established that acute moderate-intensity exercise improves cognitive performance. However, the effects of acute high-intensity aerobic exercise on cognitive performance have not been well characterized. In this review, we summarize the literature investigating the exercise-cognition interaction, especially focusing on high-intensity aerobic exercise. We discuss methodological and physiological factors that potentially mediate cognitive performance in response to high-intensity exercise. We propose that the effects of high-intensity exercise on cognitive performance are primarily affected by the timing of cognitive task (during vs. after exercise, and the time delay after exercise). In particular, cognitive performance is more likely to be impaired during high-intensity exercise when both cognitive and physiological demands are high and completed simultaneously (i.e., the dual-task paradigm). The effects may also be affected by the type of cognitive task, physical fitness, exercise mode/duration, and age. Second, we suggest that interactions between changes in regional cerebral blood flow (CBF), cerebral oxygenation, cerebral metabolism, neuromodulation by neurotransmitters/neurotrophic factors, and a variety of psychological factors are promising candidates that determine cognitive performance in response to acute high-intensity exercise. The present review has implications for recreational, sporting, and occupational activities where high cognitive and physiological demands are required to be completed concurrently.
研究論文（学術雑誌）, 英語 - Cognitive improvement after aerobic and resistance exercise is not associated with peripheral biomarkers.
Ando S; Komiyama T; Tanoue Y; Sudo M; Costello JT; Uehara Y; Higaki Y
Front Behav Neurosci, 16巻, 853150号, 掲載ページ 853150-853150, 出版日 2022年03月, 査読付, 国際誌, The role of peripheral biomarkers following acute physical exercise on cognitive improvement has not been systematically evaluated. This study aimed to explore the role of peripheral circulating biomarkers in executive performance following acute aerobic and resistance exercise. Nineteen healthy males completed a central executive (Go/No-Go) task before and after 30-min of perceived intensity matched aerobic and resistance exercise. In the aerobic condition, the participants cycled an ergometer at 40% peak oxygen uptake. In the resistance condition, they performed resistance exercise using elastic bands. Before and after an acute bout of physical exercise, venous samples were collected for the assessment of following biomarkers: adrenaline, noradrenaline, glucose, lactate, cortisol, insulin-like growth hormone factor 1, and brain-derived neurotrophic factor. Reaction time decreased following both aerobic exercise and resistance exercise (p = 0.04). Repeated measures correlation analysis indicated that changes in reaction time were not associated with the peripheral biomarkers (all p > 0.05). Accuracy tended to decrease in the resistance exercise condition (p = 0.054). Accuracy was associated with changes in adrenaline [r rm (18) = -0.51, p = 0.023], noradrenaline [r rm (18) = -0.66, p = 0.002], lactate [r rm (18) = -0.47, p = 0.035], and brain-derived neurotrophic factor [r rm (17) = -0.47, p = 0.044] in the resistance condition. These findings suggest that these peripheral biomarkers do not directly contribute to reduction in reaction time following aerobic or resistance exercise. However, greater sympathoexcitation, reflected by greater increase in noradrenaline, may be associated with a tendency for a reduction in accuracy after acute resistance exercise.
研究論文（学術雑誌）, 英語 - Effects of electrical muscle stimulation on cerebral blood flow
Ando S; Takagi Y; Watanabe H; Mochizuki K; Sudo M; Fujibayashi M; Tsurugano S; Sato K
BMC Neurosci, 22巻, 67号, 掲載ページ 67-67, 出版日 2021年11月, 査読付, 国際誌, BACKGROUND: Electrical muscle stimulation (EMS) induces involuntary muscle contraction. Several studies have suggested that EMS has the potential to be an alternative method of voluntary exercise; however, its effects on cerebral blood flow (CBF) when applied to large lower limb muscles are poorly understood. Thus, the purpose of this study was to examine the effects of EMS on CBF, focusing on whether the effects differ between the internal carotid (ICA) and vertebral (VA) arteries. METHODS: The participants performed the experiments under EMS and control (rest) conditions in a randomized crossover design. The ICA and VA blood flow were measured before and during EMS or control. Heart rate, blood pressure, minute ventilation, oxygen uptake, and end-tidal partial pressure of carbon dioxide (PETCO2) were monitored and measured as well. RESULTS: The ICA blood flow increased during EMS [Pre: 330 ± 69 mL min-1; EMS: 371 ± 81 mL min-1, P = 0.001, effect size (Cohen's d) = 0.55]. In contrast, the VA blood flow did not change during EMS (Pre: 125 ± 47 mL min-1; EMS: 130 ± 45 mL min-1, P = 0.26, effect size = 0.12). In the EMS condition, there was a significant positive linear correlation between ΔPETCO2 and ΔICA blood flow (R = 0.74, P = 0.02). No relationships were observed between ΔPETCO2 and ΔVA blood flow (linear: R = - 0.17, P = 0.66; quadratic: R = 0.43, P = 0.55). CONCLUSIONS: The present results indicate that EMS increased ICA blood flow but not VA blood flow, suggesting that the effects of EMS on cerebral perfusion differ between anterior and posterior cerebral circulation, primarily due to the differences in cerebrovascular response to CO2.
研究論文（学術雑誌）, 英語 - Effect of exercise on Brain Health: The Potential Role of Lactate as a Myokine.
Hashimoto T; Tsukamoto H; Ando S; Ogoh S
Metabolites, 11巻, 813号, 出版日 2021年11月, 査読付
研究論文（学術雑誌）, 英語 - Integrated respiratory chemoreflex-mediated regulation of cerebral blood flow in hypoxia: implications for oxygen delivery and acute mountain sickness.
Ogoh S; Washio T; Stacey BS; Tsukamoto H; Iannetelli A; Owens TS; Calverley T; Fall L; Saito S; Watanabe H; Hashimoto T; Ando S; Miyamoto T; Bailey DM
Exp Physiol, 106巻, 9号, 掲載ページ 1922-1938, 出版日 2021年07月, 査読付
研究論文（学術雑誌）, 英語 - Effects of alterations in visual flow on psychophysiological responses to virtual reality exercise.
Yasukawa K; Koike Y; Konno T; Sudo M; Ohkawara K; Ando S
Percept Mot Skills, 128巻, 3号, 掲載ページ 1169-1182, 出版日 2021年06月, 査読付, 国際誌, Virtual reality (VR) technology combined with exercise, called VR exercise, is believed to have beneficial effects on mood; but VR factors contributing to improved mood remain ambiguous. The purpose of this study was to examine the effect of visual flow speed on psychophysiological responses (i.e., physiological responses, ratings of perceived exertion or RPE, and mood) to immersive VR exercise in a simulated natural environment. Eighteen male participants (Mage =23.1, SD = 1.9 years) cycled an ergometer at 80 watts for 5 minutes on three separate occasions while watching a first-person VR movie through VR goggles at three different speeds of visual flow, corresponding to 7.5 km.h-1, 15 km.h-1, and 22.5 km.h-1. The order of the three speeds was randomized in a counterbalanced design. We measured heart rate, oxygen uptake, minute ventilation, respiratory rate, and cadence during the exercise, and we recorded ratings of perceived exertion (RPE) and mood immediately after the exercise. We evaluated mood states with the Two-Dimensional Mood Scale. One-way repeated measures analysis of variance or the Friedman test revealed no significant effects on any physiological variables, RPE or cadence as a result of altered visual flow speed during VR exercise (p > .05). However, speed of visual flow significantly influenced participant ratings of Vitality (p = 0.01) and Pleasure (p = 0.02), with the faster speed resulting in a more positive mood state. As these findings showed that VR exercise with faster visual flow induced positive mood states, we recommend faster visual flow to induce better mood states in VR exercise.
研究論文（学術雑誌）, 英語 - The effects of environmental enrichment with or without running wheel on locomotor activity and skeletal muscle volume.
Sudo M; Ando S
Bulletin of the Physical Fitness Research Institute, 119巻, 掲載ページ 9-12, 出版日 2021年04月, 査読付
研究論文（学術雑誌）, 英語 - Effects of acute interval handgrip exercise on cognitive performance.
Washio T; Suzuki K; Saito S; Watanabe H; Ando S; Brothers RM; Ogoh S
Physiol Behav, 232巻, 掲載ページ 113327-113327, 出版日 2021年04月, 査読付, 国際誌, Previous studies have reported that even a single bout of dynamic exercise improves cognitive performance. However, the acute effect of the interval handgrip (HG) exercise protocol, which is effective in reducing resting blood pressure, on cognitive performance is poorly understood. Cognitive performance was assessed in 17 young healthy subjects before and after a resting control (e.g., time control) and the interval HG exercise (Exercise), which consisted of four trials of 2-min HG exercise at 25% of maximum voluntary contraction with 3-min recovery in between each trial. Mean arterial blood pressure (MAP) and middle cerebral artery blood velocity (MCA V) were measured continuously throughout the experiment. Memory recognition and executive function were assessed using memory recognition and Go/No-Go tasks, respectively. During interval HG exercise, MAP and mean MCA V increased from the resting baseline condition (both P < 0.049) and returned to the resting baseline levels during recovery after the interval HG exercise (both P = 1.000). The reaction time and performance accuracy of the memory recognition task did not change in either the time control condition or Exercise condition (P = 0.514 and P = 0.414 respectively). However, the changes in reaction time of Go/No-Go task from the baseline in Exercise condition was significantly shorter than that in time-control condition (P = 0.004) without affecting performance accuracy (P = 0.482). The results of the present study show that an acute interval HG exercise could improve the processing speed in executive function despite no post-exercise improvement in hemodynamic parameters in young healthy subjects. These findings suggest that the interval HG exercise is a useful exercise mode that can be expected to have a positive effect on the processing speed in executive function regardless of cardiovascular adaptation to exercise.
研究論文（学術雑誌）, 英語 - Effect of intermittent isometric handgrip exercise protocol with short exercise duration on cognitive performance.
Saito S; Washio T; Watanabe H; Ando S; Ogoh S
J Physiol Sci, 71巻, 1号, 掲載ページ 12-12, 出版日 2021年04月, 査読付, 国内誌, The handgrip exercise, a small muscle exercise, is useful for exercise therapy, particularly in the elderly and bedridden patients. The isometric handgrip (IHG) exercise has been utilized in training programs to reduce resting blood pressure; however, the acute effects of the IHG exercise on cognitive performance are not fully understood. The present study aimed to investigate the effect of an intermittent IHG exercise protocol with short exercise duration, which minimizes the arterial blood pressure response to exercise, on cognitive performance. Twenty-two young healthy subjects performed the intermittent IHG exercise protocol, which consisted of 30-s IHG and 45-s recovery × 16 trials; the exercise intensity of the IHG exercise was 30% of the maximal voluntary contraction. Cognitive performance was evaluated before and after the exercise with the Go/No-Go and memory recognition tasks. Specifically, the reaction time (RT) and performance accuracy were measured. The intermittent IHG exercise protocol did not change the RT or performance accuracy of either the Go/No-Go task (P = 0.222 and P = 0.260, respectively) or the memory recognition task (P = 0.427 and P = 0.245, respectively). These findings suggest that the intermittent IHG exercise protocol with short exercise duration may not provide enough stimulation to improve cognitive performance despite being useful as a safe exercise therapy in the elderly and in patients with cardiovascular disease.
研究論文（学術雑誌）, 英語 - Plasma brain-derived neurotrophic factor and dynamic cerebral autoregulation in acute response to glycemic control following breakfast in young men.
Tsukamoto H; Ishibashi A; Marley CJ; Shinohara Y; Ando S; Bailey DM; Hashimoto T; Ogoh S
Am J Physiol Regul Integr Comp Physiol, 320巻, 1号, 掲載ページ R69-R79, 出版日 2021年01月, 査読付, 国際誌, We examined the acute impact of both low- and high-glycemic index (GI) breakfasts on plasma brain-derived neurotrophic factor (BDNF) and dynamic cerebral autoregulation (dCA) compared with breakfast omission. Ten healthy men (age 24 ± 1 yr) performed three trials in a randomized crossover order; omission and Low-GI (GI = 40) and High-GI (GI = 71) breakfast conditions. Middle cerebral artery velocity (transcranial Doppler ultrasonography) and arterial pressure (finger photoplethysmography) were continuously measured for 5 min before and 120 min following breakfast consumption to determine dCA using transfer function analysis. After these measurements of dCA, venous blood samples for the assessment of plasma BDNF were obtained. Moreover, blood glucose was measured before breakfast and every 30 min thereafter. The area under the curve of 2 h postprandial blood glucose in the High-GI trial was higher than the Low-GI trial (P < 0.01). The GI of the breakfast did not affect BDNF. In addition, both very-low (VLF) and low-frequency (LF) transfer function phase or gains were not changed during the omission trial. In contrast, LF gain (High-GI P < 0.05) and normalized gain (Low-GI P < 0.05) were decreased by both GI trials, while a decrease in VLF phase was observed in only the High-GI trial (P < 0.05). These findings indicate that breakfast consumption augmented dCA in the LF range but High-GI breakfast attenuated cerebral blood flow regulation against slow change (i.e., the VLF range) in arterial pressure. Thus we propose that breakfast and glycemic control may be an important strategy to optimize cerebrovascular health.
研究論文（学術雑誌）, 英語 - Effect of hypoxia exposure after endurance training on muscle oxidative metabolism(和訳中)
Takakura Hisashi; Takahashi Kazuya; Sudo Mizuki; Ando Soichi; Kato Hisashi; Oosawa Seita; Izawa Tetsuya
The Journal of Physical Fitness and Sports Medicine, (一社)日本体力医学会, 9巻, 6号, 掲載ページ 324-324, 出版日 2020年11月, 査読付
英語 - Hypoxia and cognitive performance – the role of barometric pressure.
Costello JT; McMorris T; Ando S; Willams TB; Corbett J
J Physiol, Cross Talk on debate巻, 出版日 2020年09月, 査読付
研究論文（学術雑誌）, 英語 - 加齢および異なる認知課題が運動と認知の二重課題のパフォーマンスに及ぼす影響
張 魯玉; 須藤 みず紀; 安藤 創一; 片山 敬章; 石田 浩司
体力科学, (一社)日本体力医学会, 69巻, 3号, 掲載ページ 306-306, 出版日 2020年06月
日本語 - Cognitive impairment during high-intensity exercise: influence of cerebral blood flow.
Komiyama T; Tanoue Y; Sudo M; Costello JT; Uehara Y; Higaki Y; Ando S
Med Sci Sports Exerc, 52巻, 3号, 掲載ページ 561-568, 出版日 2020年03月, 査読付, 国際誌, PURPOSE: Cognitive performance appears to be impaired during high-intensity exercise, and this occurs concurrently with a reduction in cerebral blood flow (CBF). However, it is unclear whether cognitive impairment during high-intensity exercise is associated with reduced CBF. We tested the hypothesis that a reduction in CBF is responsible for impaired cognitive performance during high-intensity exercise. METHODS: Using a randomized crossover design 17 healthy males performed spatial delayed response and Go/No-Go tasks in three conditions (exercise [EX], exercise+CO2 [EX+CO2], and a nonexercising control [CON]). In the EX and EX+CO2, they performed cognitive tasks at rest and during 8 min of moderate and high-intensity exercise. Exercise intensity corresponded to ~50% (moderate) and ~80% (high) of peak oxygen uptake. In the EX+CO2, the participants inspired hypercapnic gas (2% CO2) during high-intensity exercise. In the CON, they performed the cognitive tasks without exercise. RESULTS: Middle cerebral artery mean velocity increased during high-intensity exercise in the EX+CO2 relative to the EX (69.4 [10.6] cm·s, vs 57.2 [7.7] cm·s, P < 0.001). Accuracy of the cognitive tasks was impaired during high-intensity exercise in the EX (84.1% [13.3%], P < 0.05) and the EX+ CO2 (85.7 [11.6%], P < 0.05) relative to rest (EX: 95.1% [5.3%], EX+CO2: 95.1 [5.3%]). However, no differences between the EX and the EX+CO2 were observed (P > 0.10). These results demonstrate that restored CBF did not prevent cognitive impairment during high-intensity exercise. CONCLUSIONS: We conclude that a reduction in CBF is not responsible for impaired cognitive performance during high-intensity exercise.
研究論文（学術雑誌）, 英語 - The interactive effects of acute exercise and hypoxia on cognitive performance: a narrative review.
Ando S; Komiyama T; Sudo M; Higaki Y; Ishida K; Costello, JT; Katayama K
Scand J Med Sci Sports, 30巻, 3号, 掲載ページ 384-398, 出版日 2020年03月, 査読付, 国際誌, Acute moderate intensity exercise has been shown to improve cognitive performance. In contrast, hypoxia is believed to impair cognitive performance. The detrimental effects of hypoxia on cognitive performance are primarily dependent on the severity and duration of exposure. In this review, we describe how acute exercise under hypoxia alters cognitive performance, and propose that the combined effects of acute exercise and hypoxia on cognitive performance are mainly determined by interaction among exercise intensity and duration, the severity of hypoxia, and duration of exposure to hypoxia. We discuss the physiological mechanism(s) of the interaction and suggest that alterations in neurotransmitter function, cerebral blood flow, and possibly cerebral metabolism are the primary candidates that determine cognitive performance when acute exercise is combined with hypoxia. Furthermore, acclimatization appears to counteract impaired cognitive performance during prolonged exposure to hypoxia although the precise physiological mechanism(s) responsible for this amelioration remain to be elucidated. This review has implications for sporting, occupational, and recreational activities at terrestrial high altitude where cognitive performance is essential. Further studies are required to understand physiological mechanisms that determine cognitive performance when acute exercise is performed in hypoxia.
研究論文（学術雑誌）, 英語 - Effects of acute stretching on cognitive function and mood states of physically inactive young adults
Sudo M; Ando S
Percept Mot Skills, 127巻, 1号, 掲載ページ 142-153, 出版日 2020年02月, 査読付, 国際誌
研究論文（学術雑誌）, 英語 - 急性運動による認知機能の変化と機能的結合(Alterations in cognitive performance and functional connectivity induced by acute exercise)
Saito Sota; Senoo Atsushi; Wang Shan; Mizuguchi Nobuaki; Sudo Mizuki; Ohkawara Kazunori; Ando Soichi
The Journal of Physical Fitness and Sports Medicine, (一社)日本体力医学会, 8巻, 6号, 掲載ページ 272-272, 出版日 2019年11月
英語 - 認知課題の違いがデュアルタスク遂行能力に及ぼす影響(Effect of different cognitive tasks on dual-task performance)
Zhang Luyu; Sudo Mizuki; Ando Soichi; Katayama Keisho; Ishida Koji
The Journal of Physical Fitness and Sports Medicine, (一社)日本体力医学会, 8巻, 6号, 掲載ページ 272-272, 出版日 2019年11月
英語 - 自発運動は環境エンリッチメント飼育下での不安様行動を軽減する(Spontaneous locomotor activity reduces anxiety-like behavior in environmental enrichment)
Sudo Mizuki; Ando Soichi
The Journal of Physical Fitness and Sports Medicine, (一社)日本体力医学会, 8巻, 6号, 掲載ページ 284-284, 出版日 2019年11月
英語 - 運動-認知二重課題開始時の呼吸循環応答(Cardio-respiratory responses at the onset of motor-cognitive dual-task)
Ishida Koji; Zhang Luyu; Sudo Mizuki; Ando Soichi; Katayama Keisho
The Journal of Physical Fitness and Sports Medicine, (一社)日本体力医学会, 8巻, 6号, 掲載ページ 299-299, 出版日 2019年11月
英語 - One-week, but not 12-hours, cast immobilization alters promotor DNA methylation patterns in the nNOS gene in mouse skeletal muscle.
Tomiga Y; Ito A; Sudo M; Ando S; Eshima H; Sakai K; Nakashima S; Uehara Y; Tanaka H; Soejima H; Higaki Y
J Physiol, 597巻, 21号, 掲載ページ 5145-5159, 出版日 2019年11月, 査読付, 国際誌, KEY POINTS: DNA methylation may play an important role in regulating gene expression in skeletal muscle to adapt to physical activity and inactivity. Neuronal nitric oxide synthase (nNOS) in skeletal muscle is a key regulator of skeletal muscle mass; however, it is unclear whether nNOS expression is regulated by DNA methylation. We found that 1 week of cast immobilization increased nNOS DNA methylation levels and downregulated nNOS gene expression in atrophic slow-twitch soleus muscle from the mouse leg. These changes were not detected in non-atrophic fast-twitch extensor digitorum longus muscle. Twelve hours of cast immobilization decreased nNOS gene expression, whereas nNOS DNA methylation levels were unchanged, suggesting that downregulation of nNOS gene expression by short-term muscle inactivity is independent of the DNA methylation pattern. These findings contribute to a better understanding of the maintenance of skeletal muscle mass and prevention of muscle atrophy by epigenetic mechanisms via the nNOS/NO pathway. ABSTRACT: DNA methylation is a mechanism that controls gene expression in skeletal muscle under various environmental stimuli, such as physical activity and inactivity. Neuronal nitric oxide synthase (nNOS) regulates muscle atrophy in skeletal muscle. However, the mechanisms regulating nNOS expression in atrophic muscle remain unclear. We hypothesized that nNOS expression in atrophic muscle is regulated by DNA methylation of the nNOS promotor in soleus (Sol; slow-twitch fibre dominant) and extensor digitorum longus (EDL; fast-twitch fibre dominant) muscles. One week of cast immobilization induced significant muscle atrophy in Sol but not in EDL. We showed that 1 week of cast immobilization increased nNOS DNA methylation levels in Sol, although only a minor change was detected in EDL. Consistent with the increased DNA methylation levels in atrophic Sol, the gene expression levels of total nNOS and nNOSµ (i.e. the major splicing variant of nNOS in skeletal muscle) decreased. The abundance of the nNOS protein and cell membrane (especially type IIa fibre) immunoreactivity also decreased in atrophic Sol. These changes were not observed in EDL after 1 week of cast immobilization. Furthermore, despite the lack of significant atrophy, 12 h of cast immobilization decreased gene expression levels of total nNOS and nNOSµ in Sol. However, no association was detected between nNOS DNA methylation and gene expression. The expression of the nNOSβ gene, another splicing variant of nNOS, in EDL was unchanged by cast immobilization, whereas its expression was not detected in Sol. We concluded that chronic adaptation of nNOS gene expression in cast immobilized muscle may involve nNOS DNA methylation.
研究論文（学術雑誌）, 英語 - Does Exercise Improve False Episodic Memory in Dementia?
Shigehiko Ogoh; Takeshi Hashimoto; Soichi Ando
Journal of Clinical Medicine, 8巻, 1829号, 出版日 2019年11月01日, 査読付
研究論文（学術雑誌）, 英語 - Effect of acute eye fatigue on cognition for young females: A pilot study.
Akagi R; Tonotsuka M; Horie R; Hirata K; Ando S
PeerJ, 7巻, e7978号, 出版日 2019年10月, 査読付
研究論文（学術雑誌）, 英語 - Cognitive performance is associated with cerebral oxygenation and peripheral oxygen saturation, but not plasma catecholamines, during graded normobaric hypoxia
Thomas B. Williams; Jo Corbett; Terry McMorris; John S. Young; Matt Dicks; Soichi Ando; Richard C. Thelwell; Michael J. Tipton; Joseph T. Costello
Experimental Physiology, 出版日 2019年09月
研究論文（学術雑誌） - Cognitive performance is associated with cerebral oxygenation and peripheral oxygen saturation, but not plasma catecholamines, during graded normobaric hypoxia
Williams, T.B.; Corbett, J.; McMorris, T.; Young, J.S.; Dicks, M.; Ando, S.; Thelwell, R.C.; Tipton, M.J.; Costello, J.T.
Experimental Physiology, 104巻, 掲載ページ 1384-1397, 出版日 2019年09月, 査読付
研究論文（学術雑誌）, 英語 - 環境エンリッチメントにおける不安様行動の減少(Reduction in anxiety-like behavior in environmental enrichment)
Sudo Mizuki; Ando Soichi
体力研究, (公財)明治安田厚生事業団体力医学研究所, 117号, 掲載ページ 17-19, 出版日 2019年04月, 環境エンリッチメント(EE)における不安様行動(ALB)を減少する因子を明らかにするため、雄性ラットを対象としてホイール走行(WR)活動とWRの無い運動活動(LA)がALBに及ぼす影響を比較した。EEの構成物体は走行ホイール(RW)、傾斜台、トンネルおよび小屋とした。ラットは標準環境(SE群)、RWのみ存在(EE-W群)、RWのみ不在(EE-S群)、および全構成物体(EE群)の4群に分類し、各条件で6週間飼育した後、ALBを評価するため明暗探索(LDE)試験を行った。その結果、EE群の暗期中のLAはSE群やEE-S群より高く、EE-W群のLAはEE-S群より高かった。また、LDE試験ではEE-W群、EE-S群およびEE群の明期区画滞在時間がSE群より有意に長かった。以上より、WR活動とWRのないLAの両者はEEにおけるALBを低下させ、EEはALBの低下にとって有用と考えられた。
英語 - 激しい運動中の認知機能障害は脳血流量減少と関連しない(Impaired cognitive function during intense exercise is not associated with decreased cerebral blood flow)
Ando Soichi; Komiyama Takaaki; Tanoue Yukiya; Sudo Mizuki; Uehara Yoshinari; Tanaka Hiroaki; Higaki Yasuki
The Journal of Physical Fitness and Sports Medicine, (一社)日本体力医学会, 7巻, 6号, 掲載ページ 332-332, 出版日 2018年11月
英語 - 一過性運動により認知タスク中の機能的結合性が変化する(Acute exercise alters functional connectivity during cognitive task)
Saito Sota; Senoo Atsushi; Mizuguchi Nobuaki; Sudo Mizuki; Ohkawara Kazunori; Ando Soichi
The Journal of Physical Fitness and Sports Medicine, (一社)日本体力医学会, 7巻, 6号, 掲載ページ 333-333, 出版日 2018年11月
英語 - 視覚情報の変化が生理反応および心理的反応に及ぼす作用(Effects of changes in visual information on physiological and psychological response)
Konno Taisei; Yasukawa Koki; Koike Yuta; Sudo Mizuki; Ohkawara Kazunori; Ando Soichi
The Journal of Physical Fitness and Sports Medicine, (一社)日本体力医学会, 7巻, 6号, 掲載ページ 338-338, 出版日 2018年11月
英語 - 環境エンリッチメントでは運動活動の増加により認知機能が改善する(Increased exercise activity in an enriched environment improves the cognition)
Sudo Mizuki; Ando Soichi
The Journal of Physical Fitness and Sports Medicine, (一社)日本体力医学会, 7巻, 6号, 掲載ページ 339-339, 出版日 2018年11月
英語 - Does environmental enrichment increase locomotor activity in rats? Evidence from an implanted sensor device
Sudo, M.; Nagamatsu, T.; Ando, S.
Bulletin of the Physical Fitness Research Institute, 2018-April巻, 116号, 掲載ページ 29-32, 出版日 2018年04月, 査読付
研究論文（学術雑誌）, 英語 - Fixating at far distance shortens reaction time to peripheral visual stimuli at specific locations
Masahiro Kokubu; Soichi Ando; Shingo Oda
Neuroscience Letters, Elsevier Ireland Ltd, 664巻, 掲載ページ 15-19, 出版日 2018年01月18日, 査読付, The purpose of the present study was to examine whether the fixation distance in real three-dimensional space affects manual reaction time to peripheral visual stimuli. Light-emitting diodes were used for presenting a fixation point and four peripheral visual stimuli. The visual stimuli were located at a distance of 45 cm and at 25° in the left, right, upper, and lower directions from the sagittal axis including the fixation point. Near (30 cm), Middle (45 cm), Far (90 cm), and Very Far (300 cm) fixation distance conditions were used. When one of the four visual stimuli was randomly illuminated, the participants released a button as quickly as possible. Results showed that overall peripheral reaction time decreased as the fixation distance increased. The significant interaction between fixation distance and stimulus location indicated that the effect of fixation distance on reaction time was observed at the left, right, and upper locations but not at the lower location. These results suggest that fixating at far distance would contribute to faster reaction and that the effect is specific to locations in the peripheral visual field. The present findings are discussed in terms of viewer-centered representation, the focus of attention in depth, and visual field asymmetry related to neurological and psychological aspects.
研究論文（学術雑誌）, 英語 - ラット骨格筋とストレスに対する充実した環境の効果(Effects of an enriched environment on rat skeletal muscles and stress)
Sudo Mizuki; Ando Soichi; Nagamatsu Toshiya
Advances in Exercise and Sports Physiology, 日本運動生理学会, 23巻, 4号, 掲載ページ 68-68, 出版日 2017年12月
英語 - Cognitive function during exercise under severe hypoxia
Takaaki Komiyama; Keisho Katayama; Mizuki Sudo; Koji Ishida; Yasuki Higaki; Soichi Ando
SCIENTIFIC REPORTS, NATURE PUBLISHING GROUP, 7巻, 1号, 掲載ページ 10000, 出版日 2017年08月, 査読付, Acute exercise has been demonstrated to improve cognitive function. In contrast, severe hypoxia can impair cognitive function. Hence, cognitive function during exercise under severe hypoxia may be determined by the balance between the beneficial effects of exercise and the detrimental effects of severe hypoxia. However, the physiological factors that determine cognitive function during exercise under hypoxia remain unclear. Here, we examined the combined effects of acute exercise and severe hypoxia on cognitive function and identified physiological factors that determine cognitive function during exercise under severe hypoxia. The participants completed cognitive tasks at rest and during moderate exercise under either normoxic or severe hypoxic conditions. Peripheral oxygen saturation, cerebral oxygenation, and middle cerebral artery velocity were continuously monitored. Cerebral oxygen delivery was calculated as the product of estimated arterial oxygen content and cerebral blood flow. On average, cognitive performance improved during exercise under both normoxia and hypoxia, without sacrificing accuracy. However, under hypoxia, cognitive improvements were attenuated for individuals exhibiting a greater decrease in peripheral oxygen saturation. Cognitive performance was not associated with other physiological parameters. Taken together, the present results suggest that arterial desaturation attenuates cognitive improvements during exercise under hypoxia.
研究論文（学術雑誌）, 英語 - Effects of an enriched environment on rat skeletal muscles and plasma concentrations of noradrenalin and cortisol
Sudo, M.; Ando, S.; Nakanishi, Y.M.; Nagamatsu, T.
Bulletin of the Physical Fitness Research Institute, 2017-April巻, 115号, 掲載ページ 30-34, 出版日 2017年04月, 査読付
研究論文（学術雑誌）, 英語 - Repeated blood flow restriction induces muscle fiber hypertrophy
Mizuki Sudo; Soichi Ando; Yutaka Kano
MUSCLE & NERVE, WILEY, 55巻, 2号, 掲載ページ 274-276, 出版日 2017年02月, 査読付, IntroductionWe recently developed an animal model to investigate the effects of eccentric contraction (ECC) and blood flow restriction (BFR) on muscle tissue at the cellular level. This study clarified the effects of repeated BFR, ECC, and BFR combined with ECC (BFR+ECC) on muscle fiber hypertrophy.
MethodsMale Wistar rats were assigned to 3 groups: BFR, ECC, and BFR+ECC. The contralateral leg in the BFR group served as a control (CONT). Muscle fiber cross-sectional area (CSA) of the tibialis anterior was determined after the respective treatments for 6 weeks.
ResultsCSA was greater in the BFR+ECC group than in the CONT (P<0.01) and ECC (P<0.05) groups. CSA was greater in the BFR group than that in the CONT group (P<0.05).
CnclusionsThese results suggest that repeated BFR alone as well as BFR+ECC induces muscle fiber hypertrophy at the cellular level. Muscle Nerve55: 274-276, 2017
研究論文（学術雑誌）, 英語 - Effects of environmental enrichment in aged mice on anxiety-like behaviors and neuronal nitric oxide synthase expression in the brain
Yuki Tomiga; Ai Ito; Mizuki Sudo; Soichi Ando; Akino Maruyama; Shihoko Nakashima; Kentaro Kawanaka; Yoshinari Uehara; Akira Kiyonaga; Hiroaki Tanaka; Yasuki Higaki
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, 476巻, 4号, 掲載ページ 635-640, 出版日 2016年08月, 査読付, Previous studies have shown that an enriched environment (EE) has an important effect on brain function via the neuronal nitric oxide synthase/nitric oxide (nNOS/NO) pathway in young and aged animals. However, whether EE induces its effect by altering nNOS expression levels and whether it lowers anxiety-like behaviors in aged mice remains unclear. Here, we show that nNOS expression levels increased with age in the hippocampus and cerebellum in aged mice, but not in the cortex. Moreover, EE reduced anxiety-like behaviors in aged mice and reduced nNOS expression levels in the cerebellum, but not in the cortex. The present study suggests that EE improves anxiety-like behaviors in aged mice by altering nNOS expression levels in the hippocampus or cerebellum. (C) 2016 Elsevier Inc. All rights reserved.
研究論文（学術雑誌）, 英語 - Slowed response to peripheral visual stimuli during strenuous exercise
Soichi Ando; Takaaki Komiyama; Masahiro Kokubu; Mizuki Sudo; Akira Kiyonaga; Hiroaki Tanaka; Yasuki Higaki
PHYSIOLOGY & BEHAVIOR, PERGAMON-ELSEVIER SCIENCE LTD, 161巻, 掲載ページ 33-37, 出版日 2016年07月, 査読付, Recently, we proposed that strenuous exercise impairs peripheral visual perception because visual responses to peripheral visual stimuli were slowed during strenuous exercise. However, this proposal was challenged because strenuous exercise is also likely to affect the brain network underlying motor responses. The purpose of the current study was to resolve this issue. Fourteen participants performed a visual reaction-time (RT) task at rest and while exercising at 50% (moderate) and 75% (strenuous) peak oxygen uptake. Visual stimuli were randomly presented at different distances from fixation in two task conditions: the Central condition (2 degrees or 5 degrees from fixation) and the Peripheral condition (30 degrees or 50 degrees from fixation). We defined premotor time as the time between stimulus onset and the motor response, as determined using electromyographic recordings. In the Central condition, premotor time did not change during moderate (167 +/- 19 ms) and strenuous (168 +/- 24 ms) exercise from that at rest (164 +/- 17 ms). In the Peripheral condition, premotor time significantly increased during moderate (181 +/- 18 ms, P < 0.05) and strenuous exercise (189 +/- 23 ms, P < 0.001) from that at rest (173 +/- 17 ms). These results suggest that increases in Premotor Time to the peripheral visual stimuli did not result from an impaired motor-response network, but rather from impaired peripheral visual perception. We conclude that slowed response to peripheral visual stimuli during strenuous exercise primarily results from impaired visual perception of the periphery. (C) 2016 Elsevier Inc. All rights reserved.
研究論文（学術雑誌）, 英語 - Cognitive Function And Affective States Following Exercise Under Severe Hypoxia.: 1538 Board #191 June 2, 9: 00 AM - 10: 30 AM.
Sudo M; Komiya T; Nagamatsu T; Higaki Y; Ishida K; Katayama K; Ando S
Medicine and science in sports and exercise, 48巻, 5 Suppl 1号, 掲載ページ 420, 出版日 2016年05月, 査読付 - Association Between Anxiety-like Behaviors and Neuronal Nitric Oxide Synthase in Old Mice Under Enriched Environment: 3019 Board #84 June 3, 2: 00 PM - 3: 30 PM.
Tomiga Y; Ito A; Maruyama A; Sudo M; Ando S; Kawanaka K; Tanaka H; Higaki Y
Medicine and science in sports and exercise, 48巻, 5 Suppl 1号, 掲載ページ 852-853, 出版日 2016年05月, 査読付 - Reduction In Oxygen Delivery Under Severe Hypoxia Affects Cognitive Function During Moderate Exercise: 1537 Board #190 June 2, 9: 00 AM - 10: 30 AM.
Komiyama T; Katayama K; Sudo M; Ishida K; Higaki Y; Ando S
Medicine and science in sports and exercise, 48巻, 5 Suppl 1号, 掲載ページ 419, 出版日 2016年05月, 査読付 - Cognitive function at rest and during exercise following breakfast omission
Takaaki Komiyama; Mizuki Sudo; Naoki Okuda; Tetsuhiko Yasuno; Akira Kiyonaga; Hiroaki Tanaka; Yasuki Higaki; Soichi Ando
PHYSIOLOGY & BEHAVIOR, PERGAMON-ELSEVIER SCIENCE LTD, 157巻, 掲載ページ 178-184, 出版日 2016年04月, 査読付, It has been suggested that breakfast omission, as opposed to breakfast consumption, has the detrimental effects on cognitive function. However, the effects of acute exercise following breakfast omission on cognitive function are poorly understood, particularly during exercise. The purpose of this study was to examine the interactive effects of breakfast and exercise on cognitive function. Ten participants completed cognitive tasks at rest and during exercise in the breakfast consumption or omission conditions. Blood glucose concentration was measured immediately after each cognitive task. We used cognitive tasks to assess working memory [Spatial Delayed Response (DR) task] and executive function [Go/No-Go (GNG) task]. The participants cycled ergometer for 30 min while keeping their heart rate at 140 beats.min(-1). Accuracy of the GNG task was lower at rest in the breakfast omission condition than that in the breakfast consumption condition (Go trial: P = 0.012; No-Go trial: P = 0.028). However, exercise improved accuracy of the Go trial in the breakfast omission condition (P = 0.013). Reaction time in the Go trial decreased during exercise relative to rest in both conditions (P = 0.002), and the degree of decreases in reaction time was not different between conditions (P = 0.448). Exercise and breakfast did not affect the accuracy of the Spatial DR task. The present results indicate that breakfast omission impairs executive function, but acute exercise improved executive function even after breakfast omission. It appears that beneficial effects of acute exercise on cognitive function are intact following breakfast omission. (C) 2016 Elsevier Inc. All rights reserved.
研究論文（学術雑誌）, 英語 - 身体不活動者を対象としたストレッチ運動が気分と認知機能に及ぼす影響．
須藤みず紀; 安藤創一; 永松俊哉
体力研究, 公益財団法人 明治安田厚生事業団 体力医学研究所, 114巻, 掲載ページ 11-19, 出版日 2016年04月, 査読付, Chronic physical inactivity has a potential to induce negative affective states and impair cognitive function. In
contrast, it has been suggested that exercise at moderate intensity improves affective states and cognitive function.
Nevertheless, moderate exercise may induce stress responses in those who are physically inactive, which implies that moderate exercise may not be appropriate to improve affective states and cognitive function for the inactive population.
Stretching is a common form in general fitness, and may reduce anxiety and improve affective states. Hence, we
expected that acute stretching is beneficial to affective states and cognitive function, particularly in inactive people.
However, it is unclear how stretching alters affective states and cognitive function in inactive people. The purpose of this study was to examine the effects of acute stretching on affective states and cognitive function in inactive people.
Nineteen subjects participated in the present study. They performed a cognitive task（Trail Making Test: TMT）
and answered questionnaires（Mood Check List-short form 2: MCL-S.2 and WASEDA）before and after stretching
or rest （control）for 10 min. The order of stretching and control was counter-balanced. MCL-S.2 was used to assess
pleasantness, relaxation, and anxiety, and WASEDA was used to assess negative affect, positive engagement, and
tranquility. Saliva levels of immunoglobulin A（IgA）were measured before and after stretching or rest.
Reaction time in the TMT significantly decreased after stretching. Pleasantness and positive engagement increased after stretching. These alterations were not observed in the control condition. Stretching did not affect
salivary IgA. These results suggest that improvements in cognitive performance may be associated with positive
affective states induced by acute stretching. In conclusion, the present results suggest that stretching improves affective states and cognitive function in inactive people.
研究論文（学術雑誌）, 日本語 - The effects of Stretching exercise on affective states and cognitive function in inactive people
Sudo, M.; Ando, S.; Nagamatsu, T.
Bulletin of the Physical Fitness Research Institute, 114号, 出版日 2016年
研究論文（学術雑誌） - Effects of acute static stretching on visual search performance and mood state
Mizuki Sudo; Soichi Ando; Toshiya Nagamatsu
Journal of Physical Education and Sport, Editura Universitatii din Pitesti, 15巻, 4号, 掲載ページ 651-656, 出版日 2015年12月01日, 査読付, Static stretching appears to not only enhance flexibility, but also to improve mood state. However, little is known about how acute static stretching influences cognitive function. To elucidate this, we tested the hypothesis that alterations in mood state following static stretching would improve visual search performance. Sixteen participants were divided into stretching and control groups. In the stretching group, the participants answered questionnaires about mood state and performed a visual search task before and after 30 min of static stretching. In the control group, the participants rested instead of stretching. The questionnaires included items related to pleasantness, relaxation, anxiety, negative affect, positive engagement, and tranquility. We evaluated changes in cerebral hemodynamics and oxygenation during the visual search task via near-infrared spectroscopy. In the stretching group, reaction time in the visual search task decreased (P <
0.05), while response accuracy was not affected. This improvement in response speed was accompanied by increase in positive engagement (P <
0.01) and a decrease in anxiety (P <
0.05). Stretching did not modulate cerebral hemodynamics or oxygenation during the visual search task. Visual search performance was not altered in the control group. These results suggest that improved response speed is associated with an increase in positive engagement and a decrease in anxiety after static stretching.
研究論文（学術雑誌）, 英語 - The effects of temporal neck cooking on cognitive function during strenuous exercise in a hot environment: A pilot study
Soichi Ando; Takaaki Komiyama; Mizuki Sudo; Akira Kiyonaga; Hiroaki Tanaka; Yasuki Higaki
BMC Research Notes, BioMed Central Ltd., 8巻, 1号, 出版日 2015年05月30日, 査読付, Background: Heat stress potentially has detrimental effects on brain function. Hence, cognitive function may be impaired during physical activity in a hot environment. Skin cooling is often applied in a hot environment to counteract heat stress. However, it is unclear to what extent neck cooling is effective for cognitive impairment during exercise in a hot environment. The purpose of this study was to examine the effects of temporal neck cooling on cognitive function during strenuous exercise in a hot environment. Methods: Eight male young participants (mean ± SD, age = 26.1 ± 3.2 years
peak oxygen uptake = 45.6 ± 5.2 ml/kg/min) performed Spatial delayed response (DR) task (working memory) and Go/No-Go task (executive function) at rest and during exercise in the Hot and Hot + Cooling conditions. After the participants completed the cognitive tasks at rest, they cycled the ergometer until their heart rate (HR) reached 160 beats/min. Then, they cycled for 10 min while keeping their HR at 160 beats/min. The cognitive tasks were performed 3 min after their HR reached 160 beats/min. The air temperature was maintained at 35°C and the relative humidity was controlled at 70%. Neck cooling was applied to the backside of the neck by a wet towel and fanning. We used accuracy of the Spatial DR and Go/No-Go tasks and reaction time in the Go/No-Go task to assess cognitive function. Results: Neck cooling temporarily decreased the skin temperature during exercise. The accuracy of the cognitive tasks was lower during exercise than that at rest in the Hot and Hot + Cooling condition (p <
0.05). There were no differences in the accuracy between the Hot and Hot + Cooling conditions (p = 0.98). Neither exercise (p = 0.40) nor cooling (p = 0.86) affected reaction time. These results indicate that temporal neck cooling did not alter cognitive function during strenuous exercise in a hot environment. Conclusions: The present study suggests that temporal neck cooling with a wet towel and fanning is not effective for attenuating impairment of working memory and executive function during strenuous exercise with a short duration in a warm and humid environment.
研究論文（学術雑誌）, 英語 - Does moderate hypoxia alter working memory and executive function during prolonged exercise?
Takaaki Komiyama; Mizuki Sudo; Yasuki Higaki; Akira Kiyonaga; Hiroaki Tanaka; Soichi Ando
PHYSIOLOGY & BEHAVIOR, PERGAMON-ELSEVIER SCIENCE LTD, 139巻, 掲載ページ 290-296, 出版日 2015年02月, 査読付, It has been suggested that acute exercise improves cognitive function. However, little is known about how exercise under hypoxia affects cognitive function. The purpose of this study was to determine if hypoxia alters working memory and executive function during prolonged exercise. Sixteen participants performed cognitive tasks at rest and during exercise under normoxia and hypoxia [fraction of inspired oxygen (FIO2) = 0.15, corresponding to an altitude of approximately 2600 m]. The level of hypoxia was moderate. We used a combination of Spatial Delayed Response (Spatial DR) task and Go/No-Go (GNG) task, where spatial working memory and executive function are required. Working memory was assessed by the accuracy of the Spatial DR task, and executive function was assessed by the accuracy and reaction time in the GNG task. The participants cycled an ergometer for 30 min under normoxia and moderate hypoxia while keeping their heart rate (HR) at 140 beats/min. They performed the cognitive tasks 5 mm. 23 mm after their HR reached 140 beats/min. Moderate hypoxia did not alter the accuracy of the Spatial DR (P = 0.38) and GNG tasks (P = 0.14). In contrast, reaction time in the GNG task significantly decreased during exercise relative to rest under normoxia and moderate hypoxia (P = 0.02). These results suggest that moderate hypoxia and resultant biological processes did not provide sufficient stress to impair working memory and executive function during prolonged exercise. The beneficial effects on speed of response appear to persist during prolonged exercise under moderate hypoxia. (c) 2014 Elsevier Inc All rights reserved.
研究論文（学術雑誌）, 英語 - The effects of acute stretch exercise on cognitive function, cerebral oxygen dynamics, and affective state
Sudo, M.; Ando, S.; Nagamatsu, T.
Bulletin of the Physical Fitness Research Institute, 113号, 出版日 2015年
研究論文（学術雑誌） - Blood flow restriction prevents muscle damage but not protein synthesis signaling following eccentric contractions
Mizuki Sudo; Soichi Ando; David C. Poole; Yutaka Kano
Physiological Reports, American Physiological Society, 3巻, 7号, 出版日 2015年, 査読付, There is a growing body of evidence to suggest that resistance training exercise combined with blood flow restriction (BFR) increases muscle size and strength in humans. Eccentric contraction (ECC) frequently induces severe muscle damage. However, it is not known whether and to what extent muscle damage occurs following ECC + BFR due to the difficulty of conducting definitive invasive studies. The purpose of this study was to examine muscle fiber damage following ECC + BFR at the cellular level. High-intensity ECC was purposefully selected to maximize the opportunity for muscle damage and hypertrophic signaling in our novel in vivo animal model. Male Wistar rats were assigned randomly to the following groups: ECC and ECC + BFR at varying levels of occlusion pressure (140, 160, and 200 Torr). In all conditions, electrical stimulation was applied to the dorsiflexor muscles simultaneously with electromotor- induced plantar flexion. We observed severe histochemical muscle fiber damage (area of damaged fibers/total fiber area analyzed) following ECC (26.4 � 4.0%). Surprisingly, however, muscle damage was negligible following ECC + BFR140 (2.6 � 1.2%), ECC+BFR160 (3.0 � 0.5%), and ECC + BFR200 (0.2 � 0.1%). Ribosomal S6 kinase 1 (S6K1) phosphorylation, a downstream target of rapamycin (mTOR)-phosphorylation kinase, increased following ECC + BFR200 as well as ECC. In contrast, S6K1 phosphorylation was not altered by BFR alone. The present findings suggest that ECC combined with BFR, even at high exercise intensities, may enhance muscle protein synthesis without appreciable muscle fiber damage.
研究論文（学術雑誌）, 英語 - The effects of acute exercise and hypoxia on cognitive function
Soichi Ando; Takaaki Komiyama; Mizuki Sudo; Yasuki Higaki
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, ELSEVIER SCIENCE BV, 94巻, 2号, 掲載ページ 135-135, 出版日 2014年11月, 査読付
研究論文（学術雑誌）, 英語 - The effect of intense exercise on cognitive function
Takaaki Komiyama; Soichi Ando; Yoichi Hatamoto; Mizuki Sudo; Akira Kiyonaga; Hiroaki Tanaka; Yasuki Higaki
INTERNATIONAL JOURNAL OF PSYCHOPHYSIOLOGY, ELSEVIER SCIENCE BV, 94巻, 2号, 掲載ページ 222-222, 出版日 2014年11月, 査読付
研究論文（学術雑誌）, 英語 - Functional analysis of iPSC-derived myocytes from a patient with carnitine palmitoyltransferase II deficiency
Tetsuhiko Yasuno; Kenji Osafune; Hidetoshi Sakurai; Isao Asaka; Akihito Tanaka; Seiji Yamaguchi; Kenji Yamada; Hirofumi Hitomi; Sayaka Arai; Yuko Kurose; Yasuki Higaki; Mizuki Sudo; Soichi Ando; Hitoshi Nakashima; Takao Saito; Hidetoshi Kaneoka
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC ELSEVIER SCIENCE, 448巻, 2号, 掲載ページ 175-181, 出版日 2014年05月, 査読付, Introduction: Carnitine palmitoyltransferase II (CPT II) deficiency is an inherited disorder involving beta-oxidation of long-chain fatty acids (FAO), which leads to rhabdomyolysis and subsequent acute renal failure. The detailed mechanisms of disease pathogenesis remain unknown; however, the availability of relevant human cell types for investigation, such as skeletal muscle cells, is limited, and the development of novel disease models is required.
Methods: We generated human induced pluripotent stem cells (hiPSCs) from skin fibroblasts of a Japanese patient with CPT II deficiency. Mature myocytes were differentiated from the patient-derived hiPSCs by introducing myogenic differentiation 1 (MYOD1), the master transcriptional regulator of myocyte differentiation. Using an in vitro acylcarnitine profiling assay, we investigated the effects of a hypolipidemic drug, bezafibrate, and heat stress on mitochondrial FAO in CPT II-deficient myocytes and controls.
Results: CPT II-deficient myocytes accumulated more palmitoylcarnitine (C16) than did control myocytes. Heat stress, induced by incubation at 38 degrees C, leads to a robust increase of C16 in CPT II-deficient myocytes, but not in controls. Bezafibrate reduced the amount of C16 in control and CPT II-deficient myocytes.
Discussion: In this study, we induced differentiation of CPT II-deficient hiPSCs into mature myocytes in a highly efficient and reproducible manner and recapitulated some aspects of the disease phenotypes of CPT II deficiency in the myocyte disease models. This approach addresses the challenges of modeling the abnormality of FAO in CPT II deficiency using iPSC technology and has the potential to revolutionize translational research in this field. (C) 2014 Elsevier Inc. All rights reserved.
研究論文（学術雑誌）, 英語 - Does Breakfast Omission Impair Cognitive Function At Rest And During Exercise?
Soichi Ando; Takaaki Komiyama; Naoki Okuda; Mizuki Sudo; Akira Kiyonaga; Hiroaki Tanaka; Yasuki Higaki
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, LIPPINCOTT WILLIAMS & WILKINS, 46巻, 5号, 掲載ページ 214-214, 出版日 2014年05月, 査読付
研究論文（学術雑誌）, 英語 - Repeated Bouts Of Downhill Running Prevent Intense Eccentric Exercise-induced Muscle Damage In Type II Diabetes Rats
Mizuki Sudo; Soichi Ando; Yasuki Higaki; Yutaka Kano
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, LIPPINCOTT WILLIAMS & WILKINS, 46巻, 5号, 掲載ページ 755-755, 出版日 2014年05月, 査読付
研究論文（学術雑誌）, 英語 - The Effects of Exercise Under Hypoxia on Cognitive Function
Soichi Ando; Yoichi Hatamoto; Mizuki Sudo; Akira Kiyonaga; Hiroaki Tanaka; Yasuki Higaki
PLoS ONE, 8巻, 5号, 出版日 2013年05月10日, 査読付, Increasing evidence suggests that cognitive function improves during a single bout of moderate exercise. In contrast, exercise under hypoxia may compromise the availability of oxygen. Given that brain function and tissue integrity are dependent on a continuous and sufficient oxygen supply, exercise under hypoxia may impair cognitive function. However, it remains unclear how exercise under hypoxia affects cognitive function. The purpose of this study was to examine the effects of exercise under different levels of hypoxia on cognitive function. Twelve participants performed a cognitive task at rest and during exercise at various fractions of inspired oxygen (FIO2: 0.209, 0.18, and 0.15). Exercise intensity corresponded to 60% of peak oxygen uptake under normoxia. The participants performed a Go/No-Go task requiring executive control. Cognitive function was evaluated using the speed of response (reaction time) and response accuracy. We monitored pulse oximetric saturation (SpO2) and cerebral oxygenation to assess oxygen availability. SpO2 and cerebral oxygenation progressively decreased during exercise as the FIO2 level decreased. Nevertheless, the reaction time in the Go-trial significantly decreased during moderate exercise. Hypoxia did not affect reaction time. Neither exercise nor difference in FIO2 level affected response accuracy. An additional experiment indicated that cognitive function was not altered without exercise. These results suggest that the improvement in cognitive function is attributable to exercise, and that hypoxia has no effects on cognitive function at least under the present experimental condition. Exercise-cognition interaction should be further investigated under various environmental and exercise conditions. © 2013 Ando et al.
研究論文（学術雑誌）, 英語 - Peripheral visual perception during exercise: Why we cannot see
Soichi Ando
Exercise and Sport Sciences Reviews, 41巻, 2号, 掲載ページ 87-92, 出版日 2013年04月, 査読付, Peripheral visual perception may be relevant to performance in sports. Peripheral visual perception seems to be impaired during strenuous exercise. The hypothesis proposed is that a decrease in cerebral oxygenation is associated with impairment in peripheral visual perception during strenuous exercise. Recent behavioral and physiological data are presented to support the hypothesis. Copyright © 2013 by the American College of Sports Medicine.
研究論文（学術雑誌）, 英語 - The effects of exercise under hypoxia on cognitive function
Soichi Ando; Yoichi Hatamoto; Mizuki Sudo; Akira Kiyonaga; Hiroaki Tanaka; Yasuki Higaki
FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, 27巻, 掲載ページ 1973-1982, 出版日 2013年04月, 査読付
研究論文（国際会議プロシーディングス）, 英語 - Eccentric exercise-induced inflammatory response is augmented in type II diabetic skeletal muscle
Mizuki Sudo; Hiroaki Eshima; Soichi Ando; Yutaka Kano; Hiroaki Tanaka; Yasuki Higaki
FASEB JOURNAL, FEDERATION AMER SOC EXP BIOL, 27巻, 掲載ページ 214-214, 出版日 2013年04月, 査読付
研究論文（学術雑誌）, 英語 - 低酸素環境下における体内水分分布と血圧について
山下陽平; 安藤創一; 飛奈卓郎; 田中宏暁; 清永明
九州共立大学研究紀要, 3巻, 1号, 掲載ページ 47-54, 出版日 2012年09月
研究論文（大学，研究機関等紀要）, 日本語 - 女子長距離選手における気分状態と自律神経活動との関連
藤林真美; 山田陽介; 安藤創一; 中井誠一; 木村みさか; 森谷敏夫
スポーツ精神医学, 日本スポーツ精神医学会事務局, 9巻, 掲載ページ 54-58, 出版日 2012年08月22日
日本語 - Effects of strenuous exercise on visual perception are independent of visual resolution
Soichi Ando; Masahiro Kokubu; Satoshi Nakae; Misaka Kimura; Tatsuya Hojo; Naoyuki Ebine
PHYSIOLOGY & BEHAVIOR, PERGAMON-ELSEVIER SCIENCE LTD, 106巻, 2号, 掲載ページ 117-121, 出版日 2012年05月, 査読付, Strenuous exercise may have the detrimental effects on visual perception. However, it is unclear whether visual resolution is related to the detrimental effects on visual perception. The purpose of this study was to examine whether the effects of strenuous exercise on visual perception are dependent on visual resolution. Given that visual resolution decreases in the periphery of the visual field, we hypothesized that if visual resolution plays a role in the detrimental effects on visual perception, the detrimental effects may be exaggerated toward the periphery of the visual field. Simple visual reaction time was measured at rest and during cycling at 40% and 75% peak oxygen uptakes (VO2). Visual stimuli were randomly presented at 2 degrees, 10 degrees, 30 degrees, and 50 degrees to either the right or left of the midpoint between the eyes with equal probability. RT was fractionated into premotor and motor components (i.e. premotor time and motor time) based on electromyographic recording. The premotor time during exercise at 40% peak VO2 was not different from that at rest. In contrast, the premotor time during exercise at 75% peak VO2 was significantly longer than that at rest (p = 0.018). The increase in the premotor time was observed irrespective of eccentricity, and the detrimental effects were not exaggerated toward the periphery of the visual field. The motor time was not affected by exercise. The current findings suggest that the detrimental effects of strenuous exercise on visual perception are independent of visual resolution. (C) 2012 Elsevier Inc. All rights reserved.
研究論文（学術雑誌）, 英語 - PHYSICAL AND PERFORMANCE CHARACTERISTICS OF JAPANESE DIVISION 1 COLLEGIATE FOOTBALL PLAYERS
Junta Iguchi; Yosuke Yamada; Soichi Ando; Yoshihiko Fujisawa; Tatsuya Hojo; Kouji Nishimura; Kenji Kuzuhara; Yasuhiro Yuasa; Noriaki Ichihashi
JOURNAL OF STRENGTH AND CONDITIONING RESEARCH, LIPPINCOTT WILLIAMS & WILKINS, 25巻, 12号, 掲載ページ 3368-3377, 出版日 2011年12月, 査読付, Iguchi, J, Yamada, Y, Ando, S, Fujisawa, Y, Hojo, T, Nishimura, K, Kuzuhara, K, Yuasa, Y, and Ichihashi, N. Physical and performance characteristics of Japanese division 1 collegiate football players. J Strength Cond Res 25(12): 3368-3377, 2011-This study aimed to establish the physical and performance characteristics of football players in the Japanese Division 1 collegiate football program and perform a comparison of these characteristics between Japanese (n = 208) and US Division 1 football players (n = 797). The following comparisons were made: (a) between a higher-ranked university team vs. a lower-ranked university team in Japan, (b) between different playing positions in Japan, (c) between starters and nonstarters in Japan, and (d) between playing positions in Japan vs. those in the United States. The results of this study suggest that players in the higher-ranked university team were heavier, stronger in back squat, jumped higher, and had greater power than those on the lower-ranked team. Furthermore, linemen were generally characterized by larger size, greater strength, and more fat as compared with backs. On the other hand, backs tended to be faster, smaller in physical size, have higher vertical jump height, and show greater relative strength than linemen did. Starters were taller, heavier, stronger, had more powerful, and more fat-free mass than nonstarters. Finally, our results revealed that players in the United States were superior to players in Japan in all body status comparisons (p < 0.01). This study revealed that performance and superior body composition are essential for the success of a football player. Power and strength seem to be key factors in defining good football performance.
研究論文（学術雑誌）, 英語 - Does cerebral oxygenation affect cognitive function during exercise?
Soichi Ando; Masahiro Kokubu; Yosuke Yamada; Misaka Kimura
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, SPRINGER, 111巻, 9号, 掲載ページ 1973-1982, 出版日 2011年09月, 査読付, This study tested whether cerebral oxygenation affects cognitive function during exercise. We measured reaction times (RT) of 12 participants while they performed a modified version of the Eriksen flanker task, at rest and while cycling. In the exercise condition, participants performed the cognitive task at rest and while cycling at three workloads [40, 60, and 80% of peak oxygen uptake ((V) over dotO(2))]. In the control condition, the workload was fixed at 20 W. RT was divided into premotor and motor components based on surface electromyographic recordings. The premotor component of RT (premotor time) was used to evaluate the effects of acute exercise on cognitive function. Cerebral oxygenation was monitored during the cognitive task over the right frontal cortex using near-infrared spectroscopy. In the exercise condition, we found that premotor time significantly decreased during exercise at 60% peak (V) over dotO(2) relative to rest. However, this improvement was not observed during exercise at 80% peak (V) over dotO(2). In the control condition, premotor time did not change during exercise. Cerebral oxygenation during exercise at 60% peak (V) over dotO(2) was not significantly different from that at rest, while cerebral oxygenation substantially decreased during exercise at 80% peak (V) over dotO(2). The present results suggest that an improvement in cognitive function occurs during moderate exercise, independent of cerebral oxygenation.
研究論文（学術雑誌）, 英語 - Measuement of cerebral blood oxygenation during a verbal memory task by means of fNIRS
Kenji Mishima; Kiyoshi Matsuyama; Takafumi Kato; Tadashi Suetsugu; Shigeto Aramaki; Hiroaki Tanaka; Yasuki Higaki; Soichi Ando; Keiichi Irie; Sei Higuchi; Yoshiharu Akitake; Kenichi Mishima; Michihiro Fujiwara
2011 IEEE REGION 10 CONFERENCE TENCON 2011, IEEE, 掲載ページ 1212-1215, 出版日 2011年, 査読付, Functional near-infrared spectroscopy (fNIRS) was used to study changes in cerebral blood oxygenation during a verbal memory task. Eight right-handed male and six female volunteers matched on demographic variables and verbal memory performance participated in the study. Prior to verbal memory tasks, four verbal fluency tasks were loaded in order to obtain information of standard cerebral blood oxygenation for each subject. Effect of easy calculation on cerebral blood flow was examined during the verbal memory tasks. The easy calculation tasks were addition and subtraction with integer of one digit. Significant response was observed in the left prefrontal cortex, the insula bilaterally, the midline supplementary motor area, and the medial parietal cortex.
研究論文（国際会議プロシーディングス）, 英語 - Effect of rock-paper-scissors exercise on cerebral blood oxygenation during a verbal memory task measured by fNIRS
Kenji Mishima; Kiyoshi Matsuyama; Takafumi Kato; Tadashi Suetsugu; Shigeto Aramaki; Hiroaki Tanaka; Yasuki Higaki; Soichi Ando; Keiichi Irie; Sei Higuchi; Yoshiharu Akitake; Kenichi Mishima; Michihiro Fujiwara
2011 IEEE International Conference on Signal Processing, Communications and Computing, ICSPCC 2011, 出版日 2011年, 査読付, Functional near-infrared spectroscopy (fNIRS) was used to study changes in cerebral blood oxygenation during a verbal memory task. Six right-handed male and four female volunteers matched on demographic variables and verbal memory performance participated in the study. Prior to verbal memory tasks, four verbal fluency tasks were loaded in order to obtain information of standard cerebral blood oxygenation for each subject. Effect of rock-paper-scissors exercise as easy finger action on cerebral blood flow was examined during the verbal memory tasks. Significant responses were observed in the left prefrontal cortex, the insula bilaterally, the midline supplementary motor area, and the medial parietal cortex. © 2011 IEEE.
研究論文（国際会議プロシーディングス）, 英語 - 女子駅伝選手の自律神経活動とPOMS
Mami, Fujibayashi; Yosuke; Yamada, Soichi; Ando, Seiichi; Nakai; Misaka, Kimura; Toshio, Moritani
日本スポーツ精神医学, TAYLOR & FRANCIS INC, 31巻, 掲載ページ 109-109, 出版日 2010年10月, 査読付
研究論文（学術雑誌）, 英語 - キツイ運動は一瞬の判断を鈍らせるか?(運動中の認知課題のパフォーマンスからの検証)
安藤 創一; 山田 陽介; 木村 みさか
デサントスポ-ツ科学, 石本記念デサントスポ-ツ科学振興財団事務局, 31巻, 掲載ページ 125-132, 出版日 2010年06月03日
日本語 - Reaction time to peripheral visual stimuli during exercise under hypoxia
Soichi Ando; Yosuke Yamada; Masahiro Kokubu
JOURNAL OF APPLIED PHYSIOLOGY, AMER PHYSIOLOGICAL SOC, 108巻, 5号, 掲載ページ 1210-1216, 出版日 2010年05月, 査読付, Ando S, Yamada Y, Kokubu M. Reaction time to peripheral visual stimuli during exercise under hypoxia. J Appl Physiol 108: 1210-1216, 2010. First published February 18, 2010; doi:10.1152/japplphysiol.01115.2009.-The purpose of this study was to test the hypothesis that decrease in cerebral oxygenation compromises an individual's ability to respond to peripheral visual stimuli during exercise. We measured the simple reaction time (RT) to peripheral visual stimuli at rest and during and after cycling at three different workloads [40%, 60%, and 80% peak oxygen uptake ((V) over dotO(2))] under either normoxia [inspired fraction of oxygen (FI(O2)) = 0.21] or normobaric hypoxia (FI(O2)) = 0.16). Peripheral visual stimuli were presented at 10 degrees to either the right or the left of the midpoint of the eyes. Cerebral oxygenation was monitored during the RT measurement over the right frontal cortex with near-infrared spectroscopy. We used the premotor component of RT (premotor time) to assess effects of exercise on the central process. The premotor time was significantly longer during exercise at 80% peak (V)over dotO(2) (normoxia: 214.2 +/- 33.0 ms, hypoxia: 221.5 +/- 30.1 ms) relative to that at rest (normoxia: 201.0 +/- 27.2 ms, hypoxia: 202.9 +/- 29.7 ms) (P < 0.01). Under normoxia, cerebral oxygenation gradually increased up to 60% peak (V) over dotO(2) and then decreased to the resting level at 80% peak (V) over dotO(2). Under hypoxia, cerebral oxygenation progressively decreased as exercise workload increased. We found a strong correlation between increase in premotor time and decrease in cerebral oxygenation (r(2) = 0.89, P < 0.01), suggesting that increase in premotor time during exercise is associated with decrease in cerebral oxygenation. Accordingly, exercise at high altitude may compromise visual perceptual performance.
研究論文（学術雑誌）, 英語 - Effects of Exercise on Reaction Time to Peripheral Visual Stimuli
Soichi Ando
ADVANCES IN BIOMEDICAL RESEARCH, PROCEEDINGS, WORLD SCIENTIFIC AND ENGINEERING ACAD AND SOC, 掲載ページ 260-+, 出版日 2010年, 査読付, Vision is one of the most important sensory modalities in humans. Visual reaction time (RT) is the time from the appearance of a visual stimulus to the onset of motor output, and it has been used to assess perceptual and cognitive abilities in athletes. Visual field is composed of central and peripheral components. The ability to respond to peripheral visual stimuli as quickly as possible may be relevant to ball sports in which capturing visual information from the periphery of the visual field plays a role in performance. The purpose of this study was to examine effects of acute exercise under normoxia, hypoxia, and hyperoxia on the ability to respond to peripheral visual stimuli. Results showed that: (1) under normoxia, premotor component of RT (Premotor time) to peripheral visual stimuli was vulnerable to exercise as compared with that to central visual stimuli; (2) under normoxia, RT to peripheral visual stimuli increased during exercise at high workloads above the ventilatory threshold (VT) relative to that at rest, while the RT was not affected by exercise at the VT and below the VT; (3) under hypoxia, Premotor time to peripheral visual stimuli increased during exercise at low, moderate, and high workloads, and the increase in Premotor time was accompanied with decrease in cerebral oxygenation; and (4) under hyperoxia, Premotor time to peripheral visual stimuli was not different between at rest and during exercise at high workloads. These findings suggest that exercise at high workloads has detrimental effects on the ability to respond to peripheral visual stimuli unless oxygen availability was increased. Cerebral oxygenation may play a key role in visual perceptual performance during exercise.
研究論文（国際会議プロシーディングス）, 英語 - 頸髄損傷者の常酸素・低酸素環境下における軽運動時の脳内酸素動態
田中 利明; 山田 陽介; 横山 慶一; 安藤 創一; 矢部 京之助
日本生理人類学会誌, 日本生理人類学会, 14巻, 4号, 掲載ページ 157-162, 出版日 2009年11月25日, The purpose of this study was to examine cerebral oxygenation in individuals with cervical spinal cord injury (SCI) during light exercise under normoxia and hypoxia. We used near-infrared spectroscopy to measure changes in oxyhemoglobin (oxyHb), deoxyhemoglobin (deoxyHb), and total hemoglobin (totalHb). In both the SCI and Control groups, deoxyHb increased during exercise under normoxia and hypoxia relative to rest. OxyHb slightly increased during exercise in the Control group. However, oxyHb decreased during exercise under hypoxia in the SCI group. These results might come from the decreased oxygen delivering capacity in individuals with SCI which was likely to result from the autonomic nervous system dysfunction and decreased skeletal muscle pump activity, possibly due to disuse atrophy.
日本語 - The order of gaze shifts affects spatial and temporal aspects of discrete bimanual pointing movements
Masahiro Kokubu; Soichi Ando; Shingo Oda
EXPERIMENTAL BRAIN RESEARCH, SPRINGER, 198巻, 4号, 掲載ページ 501-511, 出版日 2009年10月, 査読付, We investigated whether the order of gaze shifts affected spatial and temporal aspects of discrete bimanual pointing movements. Ten male participants concurrently executed bimanual pointing movements as quickly and accurately as possible to left and right lateral targets presented with the same and different amplitudes. They were asked to gaze initially at the left target and subsequently at the right target, or vice versa. Each hand showed less variable error and a faster reaction when the initial gaze shifted to the corresponding target than when the subsequent gaze shifted to it. For the same-amplitude targets, constant error (CE) was not influenced by the gaze order conditions. However, for the different-amplitude targets, CE for the short-amplitude target became larger when they initially gazed at the long-amplitude target than when they initially gazed at the short-amplitude target. The larger overshoot of the hand for the short-amplitude target occurred when the participants could not afford to foveate the target. Our results suggest that the order of gaze shifts determines whether asymmetric amplitude assimilation between the two hands occurs or not. Fast, consistent, and accurate bimanual pointing movements might be attributable to updating gaze-centered representations of target positions.
研究論文（学術雑誌）, 英語 - Proximal electrode placement improves the estimation of body composition in obese and lean elderly during segmental bioelectrical impedance analysis
Yosuke Yamada; Yoshihisa Masuo; Keiichi Yokoyama; Yukako Hashii; Soichi Ando; Yasuko Okayama; Taketoshi Morimoto; Misaka Kimura; Shingo Oda
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, SPRINGER, 107巻, 2号, 掲載ページ 135-144, 出版日 2009年09月, 査読付, Bioelectrical impedance analysis (BIA) is an affordable, non-invasive, easy-to-operate, and fast alternative method to assess body composition. However, BIA tends to overestimate the percent body fat (%BF) in lean elderly and underestimate %BF in obese elderly people. This study examined whether proximal electrode placement eliminates this problem. Forty-two elderly men and women (64-96 years) who had a wide range of BMI [22.4 +/- A 3.3 kg/m(2) (mean +/- A SD), range 16.8-33.9 kg/m(2)] and %BF (11.3-44.8%) participated in this study. Using (2)H and (18)O dilutions as the criterion for measuring total body water (TBW), we compared various BIA electrode placements; wrist-to-ankle, arm-to-arm, leg-to-leg, elbow-to-knee, five- and nine-segment models, and the combination of distal (wrists or ankles) and proximal (elbows or knees) electrodes. TBW was most strongly correlated with the square height divided by the impedance between the knees and elbows (H (2)/Z (proximal); r = 0.965, P < 0.001). In the wrist-to-ankle, arm-to-arm, leg-to-leg, and five-segment models, we observed systematic errors associated with %BF (P < 0.05). After including the impedance ratio of the proximal to distal segments (P/D) as an independent variable, none of the BIA methods examined showed any systematic bias against %BF. In addition, all methods were able to estimate TBW more accurately (e.g., in the wrist-to-ankle model, from R (2) = 0.90, SEE = 1.69 kg to R (2) = 0.94, SEE = 1.30 kg). The results suggest that BIA using distal electrodes alone tends to overestimate TBW in obese and underestimate TBW in lean subjects, while proximal electrodes improve the accuracy of body composition measurements.
研究論文（学術雑誌）, 英語 - Single-trial reconstruction of finger-pinch forces from human motor-cortical activation measured by near-infrared spectroscopy (NIRS)
Isao Nambu; Rieko Osu; Masa-aki Sato; Soichi Ando; Mitsuo Kawato; Eiichi Naito
NEUROIMAGE, ACADEMIC PRESS INC ELSEVIER SCIENCE, 47巻, 2号, 掲載ページ 628-637, 出版日 2009年08月, 査読付, Near-infrared spectroscopy (NIRS) has recently been used to measure human motor-cortical activation, enabling the classification of the content of a sensory-motor event such as whether the left or right hand was used. Here, we advance this NIRS application by demonstrating quantitative estimates of multiple sensory-motor events from single-trial NIRS signals. It is known that different degrees of sensory-motor activation are required to generate various hand/finger force levels. Thus, using a sparse linear regression method, we examined whether the temporal changes in different force levels could be reconstructed from NIRS signals. We measured the relative changes in oxyhemoglobin concentrations in the bilateral sensory-motor cortices while participants performed an isometric finger-pinch force production with their thumb and index finger by repeatedly exerting one of three target forces (25, 50, or 75% of the maximum voluntary contraction) for 12 s. To reconstruct the generated forces, we determined the regression parameters from the training datasets and applied these parameters to new test datasets to validate the parameters in the single-trial reconstruction. The temporal changes in the three different levels of generated forces, as well as the baseline resting state, could be reconstructed, even for the test datasets. The best reconstruction was achieved when using only the selected NIRS channels dominantly located in the contralateral sensory-motor cortex, and with a four second hemodynamic delay. These data demonstrate the potential for reconstructing different levels of external loads (forces) from those of the internal loads (activation) in the human brain using NIRS. (C) 2009 Elsevier Inc. All rights reserved.
研究論文（学術雑誌）, 英語 - Reaction time to peripheral visual stimuli during exercise under normoxia and hyperoxia
Soichi Ando; Yosuke Yamada; Toshiaki Tanaka; Shingo Oda; Masahiro Kokubu
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, SPRINGER, 106巻, 1号, 掲載ページ 61-69, 出版日 2009年05月, 査読付, The purpose of this study was to test if increased oxygen availability affected simple reaction time (RT) to peripheral visual stimuli during exercise. Twelve male participants performed RT tasks at rest, during cycling with three different workloads (100, 150, and 200 W), and after exercise. We fractionated RT into Premotor time and Motor time. Under normoxia, Premotor time significantly increased during exercise at 200 W (mean +/- A SD, 224.7 +/- A 34.8 ms) relative to that at rest (213.3 +/- A 34.1 ms) (P < 0.05). In contrast, we found no difference in Premotor time between at rest (214.0 +/- A 27.0 ms) and at 200 W (213.0 +/- A 21.6 ms) under hyperoxia. Furthermore, Premotor time significantly decreased at 150 W (201.3 +/- A 22.4 ms) relative to that at rest under hyperoxia (P < 0.05). These results suggest that increased oxygen availability during exercise has beneficial effects on perceptual performance.
研究論文（学術雑誌）, 英語 - Effects of Acute Exercise on Visual Reaction Time
S. Ando; M. Kokubu; T. Kimura; T. Moritani; M. Araki
INTERNATIONAL JOURNAL OF SPORTS MEDICINE, GEORG THIEME VERLAG KG, 29巻, 12号, 掲載ページ 994-998, 出版日 2008年12月, 査読付, We examined the effects of acute exercise on reaction time to Visual stimuli presented in the central portion and periphery of the visual field. Twelve participants performed reaction time tasks at rest and during cycling at 65% peak oxygen uptake in two visual conditions. We used circular black-and-white checkerboard patterns as visual Stimuli. The participants were asked to respond as quickly as possible to pattern reversal of the visual Stimulus by releasing a response button. Reaction time was fractionated into Premotor time and Motor time. Premotor time in the peripheral condition significantly increased (p < 0.025) during exercise (mean +/- SE; 195.9 +/- 7.9 ms) from that at rest (183.7 +/- 6.8 ms). Premotor time in the central condition did not differ between at rest (185.3 +/- 7.6 ms) and during exercise (188.4 +/- 6.6 ms). These data suggest that the ability to respond to visual stimuli presented in the periphery of the visual field is vulnerable to moderate to severe exercise, as compared with the ability to respond to visual stimuli presented in the central portion of the visual field. An exercise-induced increase in arousal level and a consequent narrowing of attentional focus would explain the present results.
研究論文（学術雑誌）, 英語 - The effect of fixation distance on reaction times for the peripheral visual field
Masahiro Kokubu; Soichi Ando; Shingo Oda
JOURNAL OF SPORT & EXERCISE PSYCHOLOGY, HUMAN KINETICS PUBL INC, 29巻, 掲載ページ S99-S100, 出版日 2007年06月, 査読付
研究論文（国際会議プロシーディングス）, 英語 - Prediction for finger force from cortical activity measured by near-infrared spectroscopy (NIRS)
Isao Nambu; Rieko Osu; Soichi Ando; Eiichi Naito; Mitsuo Kawato
NEUROSCIENCE RESEARCH, ELSEVIER IRELAND LTD, 58巻, 掲載ページ S128-S128, 出版日 2007年, 査読付
研究論文（国際会議プロシーディングス）, 英語 - Increase in reaction time for the peripheral visual field during exercise above the ventilatory threshold
S Ando; T Kimura; T Hamada; M Kokubu; T Moritani; S Oda
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, SPRINGER, 94巻, 4号, 掲載ページ 461-467, 出版日 2005年07月, 査読付, The purpose of the present study was to determine whether reaction time (RT) for the peripheral visual field increases at exercise intensity above the ventilatory threshold (VT) during incremental exercise and to examine the relationship between aerobic capacity and the extent of increase in the RT. Nine healthy subjects performed a simple manual RT task for the peripheral visual field at rest, during exercise on a cycle ergometer, and immediately after exercise. After warm-up exercise, the subjects cycled at 40 W for 3 min, increasing by 40 W every 3 min until 240 W in a step-wise manner. During incremental exercise, RT measurements were performed 1 min and 30 s after the start of every increase in workload. The RT for the peripheral visual field significantly increased at exercise intensity above VT, as compared with at rest. The increase in the RT, which was calculated by subtracting the RT at rest from the RT at 240 W, negatively correlated with maximal oxygen uptake (<(V)overdot > O-2max) for each subject (r = -0.73, P < 0.05). It is likely that high aerobic capacity attenuates the increase in the RT for the peripheral visual field during exhaustive exercise.
研究論文（学術雑誌）, 英語 - Retention of practice effects on simple reaction time for peripheral and central visual fields
S Ando; N Kida; S Oda
PERCEPTUAL AND MOTOR SKILLS, PERCEPTUAL MOTOR SKILLS, 98巻, 3号, 掲載ページ 897-900, 出版日 2004年06月, 査読付, Previous researchers reported that EMG Reaction Time (RT) for a key press in peripheral and central visual fields decreases with practice. The practice effects on the RT for peripheral visual field transferred to the RT for the central visual field, and vice versa. The present study investigated whether practice effects on the RT for peripheral and central visual fields and the corresponding transfer effects lasted 3 wk. or not. 16 male subjects were divided into two groups, one practicing using peripheral vision, the other practicing using central vision. Each group practiced RT tasks for 3 wk. 3 wk. after practice terminated, the practice effects and the transfer effects were maintained as a significant decrease in RT was found over the 3-wk. retention interval, suggesting that once the neural correlates of responding quickly are improved, the improved performances are remarkably stable for at least 3 wk.
研究論文（学術雑誌）, 英語 - Attention can be oriented to intermediate locations within the large area of the visual field
S Ando; M Kokubu; N Kida; S Oda
PERCEPTUAL AND MOTOR SKILLS, PERCEPTUAL MOTOR SKILLS, 95巻, 3号, 掲載ページ 806-812, 出版日 2002年12月, 査読付, The present study examined whether attention can be evenly distributed within the large area of the visual field. The stimulus was presented at one of four locations on the horizontal meridian (0degrees, 10degrees, 20degrees, and 30degrees to the right). In the Fixed Location condition, the stimulus appeared repeatedly at the same location. In the Random Location condition, the stimulus appeared at one of four locations as determined randomly with equal probability. Reaction times (RTs) in the Random Location condition were significantly longer than those in the Fixed Location condition at the 0degrees and 30degrees locations, while there were no significant differences at the 10degrees and 20degrees locations. The differences in the RT between conditions were significantly larger at the 0degrees and 30degrees locations than those at the 10degrees and 20degrees locations. These-results suggest that attention was oriented to intermediate locations within the large area of the visual field.
研究論文（学術雑誌）, 英語 - Practice effects on reaction time for peripheral and central visual fields
S Ando; N Kida; S Oda
PERCEPTUAL AND MOTOR SKILLS, PERCEPTUAL MOTOR SKILLS, 95巻, 3号, 掲載ページ 747-751, 出版日 2002年12月, 査読付, The present study examined whether EMG-RT (RT) for a key press to stimulus in peripheral and central visual fields decreases with practice. 16 male students were divided into two groups, one practicing using peripheral vision, the other practicing using central vision. Before and after practice, RT was measured for peripheral and central visual fields. Each group practiced three blocks of 25 trials five days a week for three weeks. RT for peripheral and central visual fields decreased with practice. Practice effects on RT for the peripheral visual field extended to RT for the central visual field, and vice versa. It is suggested that the transfer may reflect the decrease in the central nervous system's processing time in common between two RT tasks.
研究論文（学術雑誌）, 英語 - Central and peripheral visual reaction time of soccer players and nonathletes
S Ando; N Kida; S Oda
PERCEPTUAL AND MOTOR SKILLS, PERCEPTUAL MOTOR SKILLS, 92巻, 3号, 掲載ページ 786-794, 出版日 2001年06月, 査読付, Visual Reaction Time (RT) was measured by presenting three different sizes of stimulus to the central and peripheral fields of vision in 6 soccer players and 6 nonathletes. An electromyogram was recorded from the flexor digitorum superficialis muscle of the responding forearm. Peripheral visual RT was longer in comparison to central visual RT due to an increment in Premotor Time. The soccer players showed shorter Premotor Times during central and peripheral visual RT tasks than nonathletes, suggesting that the soccer players are better able to respond quickly to a stimulus presented to peripheral as well as central positions.
研究論文（学術雑誌）, 英語 - サッカー選手と一般学生における中心視野と周辺視野の反応時間
安藤創一; 来田宣幸; 小田伸午
京都体育学研究, 京都体育学会, 15巻, 掲載ページ 7-13, 出版日 1999年07月, 査読付, Visual reaction time of 20 soccer players and 13 nonathlete university students was measured using three different sizes of stimulus in central and peripheral vision.The results were summarized as follows: 1) Central visual reaction time of soccer players increased significantly with a decrease in size of a stimulus, while peripheral visual reaction time of nonathletes increased significantly with a decrease in size of the stimulus.2) In soccer players the correlation between peripheral visual reaction time and central visual reaction time was higher when the size of the stimulus was small. In nonathletes，however，correlation of the same parameters was higher when the size of the stimulus was large. These results suggest that soccer players have a higher ability of peripheral visual perception to the smaller object than nonathletes，that might enable to make quick judgement and decision to the far distant ball in the soccer field.
研究論文（学術雑誌）, 日本語
MISC
- 骨格筋への電気刺激はどこまで運動の代替となるか?応用可能性の検証
安藤 創一; 岡本 孝信; 橋本 佑斗
(公財)石本記念デサントスポーツ科学振興財団, 出版日 2024年02月, デサントスポーツ科学, 45巻, 掲載ページ 3-11, 日本語, 査読付, 速報，短報，研究ノート等（学術雑誌）, 0285-5739, 2758-4429, Y229430001 - 低酸素トレーニングはどこまで進化したか?:斬新な発想による新しいチャレンジ 低酸素環境での運動による認知パフォーマンスの変化とその低下の予防法
安藤 創一
(一社)日本体力医学会, 出版日 2023年02月, 体力科学, 72巻, 1号, 掲載ページ 21-21, 日本語, 査読付, 研究発表ペーパー・要旨（全国大会，その他学術会議）, 0039-906X, 1881-4751, 2023161354 - 運動による脳機能の向上と、神経修飾物質を介した脳機能調節メカニズム 運動による認知パフォーマンスの向上 ドーパミンの関与
安藤 創一; 藤本 敏彦; 田代 学
(一社)日本体力医学会, 出版日 2022年02月, 体力科学, 71巻, 1号, 掲載ページ 57-57, 日本語, 査読付, 研究発表ペーパー・要旨（全国大会，その他学術会議）, 0039-906X, 1881-4751, 2022109678 - 脳の微小構造に対する一過性運動の影響
SHINODA Ayato; KATAGIRI Yuki; MIZUGUCHI Nobuaki; MOCHIZUKI Kouta; SUDOU Mizuki; OHKAWARA Kazunori; SENOO Atsushi; ANDO Soichi
出版日 2022年, Journal of Physical Fitness and Sports Medicine, 11巻, 6号, 査読付, 研究発表ペーパー・要旨（全国大会，その他学術会議）, 2186-8131, 202202233282594120 - 一過性有酸素運動による認知機能増強と機能的結合との関係
ISHIMURA Kento; KATAGIRI Yuki; MIZUGUCHI Nobuaki; MOCHIZUKI Kouta; SUDOU Mizuki; OHKAWARA Kazunori; SENOO Atsushi; ANDO Soichi
出版日 2022年, Journal of Physical Fitness and Sports Medicine, 11巻, 6号, 査読付, 研究発表ペーパー・要旨（全国大会，その他学術会議）, 2186-8131, 202202242795025479 - 局所の骨格筋への電気刺激が気分・感情に与える影響:随意運動との比較
須藤みず紀; 安藤創一
出版日 2021年, 体力研究, 119号, 査読付, 速報，短報，研究ノート等（学術雑誌）, 0389-9071, 202102246678205146 - なぜ運動による覚醒レベルの上昇は認知パフォーマンスを高めるのか?
安藤 創一
本研究の目的は,運動による覚醒レベルの上昇が認知パフォーマンスを向上させるメカニズム解明のために,運動による覚醒レベルの向上に関わる脳領域を同定すること,脳領域間の機能的結合の変化が覚醒レベルの変化に関与するかを明らかにすることであった.18名の実験参加者は,最高酸素摂取量の40%の運動強度での運動前後,および安静の前後に認知課題を行い,fMRIを用いて脳活動を撮像した.運動後に覚醒レベルは上昇し,認知パフォーマンスは向上した.運動による覚醒レベルの変化は,準備刺激に対する左下前頭回,右前頭極,および右背側帯状回皮質の活動増加と関係がみられた.さらに,覚醒レベルの変化は,これらの領域間での機能的結合の増加を伴っていた.本研究から,運動による覚醒レベルの上昇には,前頭前野,前頭極,帯状回皮質の領域間の神経ネットワークが関与し,この領域間のネットワークが高まることが認知パフォーマンスの向上に貢献することが示唆された.(著者抄録), (公財)石本記念デサントスポーツ科学振興財団, 出版日 2020年09月, デサントスポーツ科学, 41巻, 掲載ページ 3-9, 日本語, 0285-5739, 2758-4429, 2021110392 - 加齢および異なる認知課題が運動と認知の二重課題のパフォーマンスに及ぼす影響
張魯玉; 須藤みず紀; 安藤創一; 片山敬章; 石田浩司
出版日 2020年, 体力科学, 69巻, 3号, 0039-906X, 202002249873811129 - Effect Of Isometric Handgrip Exercise On Hypercapnia-induced Shear-mediated Dilation In The Internal Carotid Artery
Takuro Washio; Kazuya Suzuki; Takashi Yamagata; Soichi Ando; Shigehiko Ogoh
LIPPINCOTT WILLIAMS & WILKINS, 出版日 2019年06月, MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 51巻, 6号, 掲載ページ 671-671, 英語, 研究発表ペーパー・要旨（国際会議）, 0195-9131, 1530-0315, WOS:000481662802487 - 一過性運動による認知課題中の機能的結合の変化
齋藤颯太; 妹尾淳史; 水口暢章; 須藤みず紀; 大河原一憲; 安藤創一
出版日 2018年09月, 第73回体力医学会大会抄録 - Acute Stretching Improves Affective States And Cognitive Function In Physically Inactive People.
Mizuki Sudo; Soichi Ando; Yuki Tomiga; Toshiya Nagamatsu
LIPPINCOTT WILLIAMS & WILKINS, 出版日 2017年05月, MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 49巻, 5号, 掲載ページ 303-303, 英語, 研究発表ペーパー・要旨（国際会議）, 0195-9131, 1530-0315, WOS:000415214600108 - Effects Of Aerobic And Resistance Exercise On Cognitive Function.
Takaaki Komiyama; Kenji Ando; Mizuki Sudo; Ryuji Takigawa; Kazunori Ohkawara; Yoshinari Uehara; Hiroaki Tanaka; Yasuki Higaki; Soichi Ando
LIPPINCOTT WILLIAMS & WILKINS, 出版日 2017年05月, MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 49巻, 5号, 掲載ページ 698-698, 英語, 研究発表ペーパー・要旨（国際会議）, 0195-9131, 1530-0315, WOS:000415215700437 - Cognitive Function After Exhaustive Exercise: Effects Of Cerebral Oxygenation
Soichi Ando; Mizuki Sudo; Takaaki Komiyama; Ryo Aoyagi; Yasuki Higaki
LIPPINCOTT WILLIAMS & WILKINS, 出版日 2017年05月, MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 49巻, 5号, 掲載ページ 696-696, 英語, 研究発表ペーパー・要旨（国際会議）, 0195-9131, 1530-0315, WOS:000415215700431 - 高強度運動時に認知機能の低下が起こるのはなぜか : 脳血流と脳酸素動態からの検証
小見山 高明; 檜垣 靖樹; 安藤 創一; 須藤 みず紀
高強度運動時の認知機能の低下に関わる要因として、脳血流と脳酸素飽和度が関与している可能性がある。本研究では、15名の健常成人男性(年齢:23.3±1.8歳、身長:1.70±0.06m、体重:64.4±5.8kg、最高酸素摂取量:47.3±6.4ml/kg/min)を対象に、中強度及び高強度の運動中に認知課題を実施し、同時に中大脳動脈血流速度と前頭前野の脳酸素飽和度の測定を行い、高強度運動時の認知機能の低下と脳血流及び脳酸素飽和度の変化との関係性を明らかにすることを目的とした。高強度運動時には、安静時及び中強度運動時と比較して認知課題の正解率は有意な低下が認められた(安静時:P<0.05、中強度運動時:P<0.01)。一方で反応時間に有意な差は認められなかった(P=0.31)。脳血流速度は安静時と比較して中強度運動時に増加し(P<0.01)、高強度運動時では中強度運動時と比較して有意な低下がみられた(P<0.01)。脳酸素飽和度は安静時と比較して高強度運動時に低下する傾向が認められた(P=0.058)。したがって、高強度運動時の脳血流や脳酸素飽和度の低下は、認知機能の低下に関与している可能性が示唆された。(著者抄録), 石本記念デサントスポーツ科学振興財団事務局, 出版日 2017年05月, デサントスポーツ科学, 38巻, 掲載ページ 207-215, 日本語, 0285-5739, 2758-4429, 2018065236, 40021225780 - 豊かな環境が骨格筋と生理的ストレス応答に及ぼす影響
須藤みず紀; 安藤創一; 永松俊哉
出版日 2017年, 日本運動生理学会大会プログラム・抄録集, 25th巻, 201702247829994523 - 低酸素環境における運動中の動脈血酸素飽和度の低下は認知機能の向上を減弱させる
小見山高明; 片山敬章; 須藤みず紀; 石田浩司; 檜垣靖樹; 安藤創一
出版日 2017年, 日本運動生理学会大会プログラム・抄録集, 25th巻, 201702251110492741 - 低酸素環境での運動が認知機能に与える影響 (特集 低酸素環境によるヒューマン・ハイ・パフォーマンス)
小見山 高明; 安藤 創一
杏林書院, 出版日 2016年12月, 体育の科学, 66巻, 12号, 掲載ページ 886-890, 日本語, 0039-8985, 40021016735, AN00135823 - 運動による認知機能の向上は運動様式によって異なるのか?
安藤 創一
石本記念デサントスポーツ科学振興財団事務局, 出版日 2016年06月, デサントスポーツ科学, 37巻, 掲載ページ 130-137, 日本語, 0285-5739, 40020876309, AN00357177 - ICP-MSによる細胞内外液測定の妥当性
山田 陽介; 走井 裕香子; 安藤 創一; 糸井 亜弥; 吉川 豊; 安井 裕之; 森本 武利; 木村 みさか
(一社)日本体力医学会, 出版日 2015年12月, 体力科学, 64巻, 6号, 掲載ページ 672-672, 日本語, 0039-906X, 1881-4751, 2016136283 - 1回の運動が感情状態に及ぼす効果はどこまで続くのか?
安藤創一; 小見山高明; 青柳遼; 畑本陽一; 須藤みず紀; 檜垣靖樹
(一社)日本体力医学会, 出版日 2015年12月01日, 体力科学, 64巻, 6号, 掲載ページ 540-540, 日本語, 0039-906X, 1881-4751, 2016135789, 201602209184063496 - 組織及び筋線維タイプにおけるnNOSのDNAメチル化修飾に関する研究
伊藤愛; 冨賀裕貴; 須藤みず紀; 安藤創一; 中島志穂子; 田中宏暁; 檜垣靖樹
出版日 2015年12月01日, 体力科学, 64巻, 6号, 掲載ページ 553, 日本語, 0039-906X, 201602214084159031 - Acute Stretching Improves Affective States And Cognitive Function In Physically Inactive People
Mizuki Sudo; Soichi Ando; Yuki Tomiga; Toshiya Nagamatsu
LIPPINCOTT WILLIAMS & WILKINS, 出版日 2015年05月, MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 47巻, 5号, 掲載ページ 303-303, 英語, 研究発表ペーパー・要旨（国際会議）, 0195-9131, 1530-0315, WOS:000415220100108 - 1回の運動がもたらすメンタルヘルスへの有益な効果はどの程度続くのか?
安藤 創一; 小見山 高明; 畑本 陽一
明治安田厚生事業団, 出版日 2015年04月, 若手研究者のための健康科学研究助成成果報告書 = Research-aid report, 30巻, 掲載ページ 11-15, 日本語, 40021134461 - 一過性のストレッチ運動が認知機能、脳の酸素化動態、および感情に及ぼす影響
須藤 みず紀; 安藤 創一; 永松 俊哉
健常若年男性16名を被験者とし、静的ストレッチで構成された運動プログラムを30分間実施する群8名(ストレッチ群)と対照群8名に振り分け、「認知機能(視覚探索課題で評価)」「脳の酸素化動態」「感情(MCL-S.2とWASEDAで評価)」の変化を群間比較した。結果、ストレッチ群は対照群に比べて視覚探索課題での反応時間が有意に短縮し、またMCL-S.2における[不安感]が有意に低下、WASEDAにおける[高揚感]が有意に上昇した。, (公財)明治安田厚生事業団体力医学研究所, 出版日 2015年04月, 体力研究, 113号, 掲載ページ 19-26, 日本語, 0389-9071, 2016078031 - 身体活動が骨格筋に及ぼす影響
安藤 創一; 須藤 みず紀; 道下 竜馬
福岡大学研究推進部, 出版日 2015年03月, 福岡大学研究部論集. F, 推奨研究編 : 推奨研究プロジェクト成果報告書 = The bulletin of Central Research Institute Fukuoka University, 2巻, 掲載ページ 205-208, 日本語, 2188-5354, 120005661307 - マウス片側後肢ギプス固定モデルの非固定脚を対照脚として用いることの問題
冨賀 裕貴; 須藤 みず紀; 安藤 創一; 江島 弘晃; 桧垣 靖樹
加齢に伴う廃用性筋萎縮(サルコペニア)モデル作出を目的としたギプス固定マウスの有用性を検証した。1週間片脚ギプス固定後遅筋線維から構成されるヒラメ筋(Sol),速筋線維から構成される足底筋(Pla)を抽出し,筋重量を計測した。無処置マウスでは実験実施前後において体重に変化が見られなかったが,ギプス固定マウスでは処置後で有意な体重減少を認め,各筋の体重あたりの筋重量も顕著に減少していた。体重減少は固定による精神的ストレス,食欲減退も考えられるが,食餌摂取量は無処置対照群と差異はなく,体重減少も2週間で正常化した。短期ギプス固定は筋萎縮誘発には有効であるが,非固定脚の代償的負荷の影響や骨格筋細胞レベルでの変化を検証する必要性を示唆した。, 福岡大学, 出版日 2015年03月, 福岡大学スポーツ科学研究, 45巻, 2号, 掲載ページ 53-58, 日本語, 1345-9244, 2015224194, 110009889022 - 疲労困憊運動による心理的・生理学的作用が認知機能に及ぼす影響
須藤みず紀; 小見山高明; 青柳遼; 桧垣靖樹; 永松俊哉; 安藤創一
(一社)日本体力医学会, 出版日 2014年12月01日, 体力科学, 63巻, 6号, 掲載ページ 547-547, 日本語, 0039-906X, 1881-4751, 2015150574, 201502272793761405 - 高強度運動が認知機能に及ぼす影響
小見山高明; 安藤創一; 畑本陽一; 須藤みず紀; 清永明; 田中宏暁; 桧垣靖樹
(一社)日本体力医学会, 出版日 2014年12月01日, 体力科学, 63巻, 6号, 掲載ページ 541-541, 日本語, 0039-906X, 1881-4751, 2015150550, 201502281247092453 - 高強度の運動中にみられる周辺視野での反応の遅延は知覚能力の低下である
安藤創一; 小見山高明; 國部雅大; 須藤みず紀; 清永明; 田中宏暁; 桧垣靖樹
(一社)日本体力医学会, 出版日 2014年12月01日, 体力科学, 63巻, 6号, 掲載ページ 539-539, 日本語, 0039-906X, 1881-4751, 2015150543, 201502284002639634 - 2型糖尿病骨格筋におけるダウンヒルトレーニングは運動誘発性筋損傷を抑制する
須藤みず紀; 安藤創一; 冨賀裕貴; 三好耕太; 田中宏暁; 狩野豊; 桧垣靖樹
出版日 2013年12月01日, 体力科学, 62巻, 6号, 掲載ページ 599, 日本語, 0039-906X, 201402226436052375 - 朝食摂取は運動中の認知機能に影響を与えるのか?
安藤創一; 小見山高明; 奥田尚紀; 須藤みず紀; 清永明; 田中宏暁; 桧垣靖樹
(一社)日本体力医学会, 出版日 2013年12月01日, 体力科学, 62巻, 6号, 掲載ページ 497-497, 日本語, 0039-906X, 1881-4751, 2014155289, 201402228845407587 - P-8 Cognitive function during strenuous exercise in a hot environment(The Proceedings of the 21st Annual Meetings of Japan Society of Exercise and Sports Physiology July 27 ・ 28, (Saitama)) :
ANDO Soichi; KOMIYAMA Takaaki; SUDO Mizuki; KIYONAGA Akira; TANAKA Hiroaki; HIGAKI Yasuki
Japan Society of Exercise and Sports Physiology, 出版日 2013年, Advances in exercise and sports physiology, 19巻, 4号, 掲載ページ 123-123, 英語, 1340-3141, 110009687794, AA11107566 - 高温環境下における運動中の認知機能
安藤創一; 小見山高明; 須藤みず紀; 清永明; 田中宏暁; 桧垣靖樹
出版日 2013年, 日本運動生理学会大会プログラム・抄録集, 21st巻, 掲載ページ 86, 日本語, 201402229802269721 - エキセントリック収縮誘発性の炎症応答は2型糖尿病において増大する
須藤みず紀; 安藤創一; 清永明; 田中宏暁; 狩野豊; 桧垣靖樹
出版日 2012年12月01日, 体力科学, 61巻, 6号, 掲載ページ 578, 日本語, 0039-906X, 201302258702261467 - 1週間のマウス片脚ギプス固定誘発性筋萎縮は筋線維タイプにより異なる
冨賀裕貴; 津布子拓弥; 江島弘晃; 安藤創一; 須藤みず紀; 田中宏暁; 桧垣靖樹
出版日 2012年12月01日, 体力科学, 61巻, 6号, 掲載ページ 581, 日本語, 0039-906X, 201302299471581020 - 低酸素環境下での運動は認知機能を低下させるか?
安藤創一; 畑本陽一; 須藤みず紀; 清永明; 田中宏暁; 桧垣靖樹
出版日 2012年, 日本運動生理学会大会プログラム・抄録集, 20th巻, 掲載ページ 59, 日本語, 201202214925899264 - マウス片側後肢ギプス固定による筋萎縮モデルの確立
冨賀裕貴; 須藤みず紀; 安藤創一; 江島弘晃; 清永明; 田中宏暁; 桧垣靖樹
出版日 2011年12月01日, 体力科学, 60巻, 6号, 掲載ページ 614, 日本語, 0039-906X, 201202254611796551 - 女子アスリートにおける心身の関連
藤林真美; 山田陽介; 安藤創一; 中井誠一; 木村みさか; 森谷敏夫
出版日 2011年08月15日, スポーツ精神医学, 8巻, 掲載ページ A22, 日本語, 1349-4929, 201102206603607306 - 03心-2A-K13 女子トップアスリートにおける自律神経活動と心理面との関連(03.体育心理学,一般研究発表抄録)
藤林 真美; 山田 陽介; 安藤 創一; 中井 誠一; 木村 みさか; 森谷 敏夫
社団法人日本体育学会, 出版日 2010年09月08日, 日本体育学会大会予稿集, 61巻, 61号, 日本語, 110008086844 - 04生-3P-P14 運動時における脳の組織酸素飽和度の変化は認知機能に影響を与えるか?(04.運動生理学,一般研究発表抄録)
安藤 創一; 國部 雅大; 山田 陽介; 木村 みさか
社団法人日本体育学会, 出版日 2010年09月08日, 日本体育学会大会予稿集, 61巻, 61号, 日本語, 110008086950 - こどもの足型に見られる問題と身体活動との関係―都市部小学校6年生児童における調査から―
糸井亜弥; 木村みさか; 走井裕香子; 安藤創一; 櫻井寿美; 山田陽介; 中江悟司; 諏佐準一
出版日 2010年03月10日, 日本発育発達学会大会抄録集, 8th巻, 掲載ページ 95, 日本語, 201002213963409237 - 高酸素環境下での運動中の周辺視野反応時間
安藤創一; 山田陽介; 小田伸午; 國部雅大
出版日 2009年12月01日, 体力科学, 58巻, 6号, 掲載ページ 742, 日本語, 0039-906X, 201002284243518203 - 様々な対象に適用できる簡易身体活動量評価法(女子大生及び大学女子ランナーでの検討)
走井裕香子; 山田陽介; 安藤創一; 木村みさか
出版日 2009年09月17日, 肥満研究, 15巻, Supplement号, 掲載ページ 239, 日本語, 1343-229X, 201002218697359875 - 1-O-23 Reaction time to peripheral visual stimuli during exercise under normoxia and hypoxia(The Proceedings of the 17th Annual Meetings of Japan Society of Exercise and Sports Physiology Jury 25-26, (Tokyo)) :
ANDO Soichi; YAMADA Yosuke; KOKUBU Masahiro
Japan Society of Exercise and Sports Physiology, 出版日 2009年, Advances in exercise and sports physiology, 15巻, 2号, 掲載ページ 59-59, 英語, 1340-3141, 110007574325, AA11107566 - 運動中になぜ周辺視野での反応の早さが低下するのか?
安藤創一; 山田陽介; 國部雅大
出版日 2009年, 日本運動生理学会大会プログラム・抄録集, 17th巻, 掲載ページ 67, 日本語, 200902238981858873 - Reconstruction of finger force from NIRS signal-Methodological perspective
Isao Nambu; Rieko Osu; Soichi Ando; Masa-aki Sato; Eiichi Naito; Mitsuo Kawato
ELSEVIER IRELAND LTD, 出版日 2008年, NEUROSCIENCE RESEARCH, 61巻, 掲載ページ S212-S212, 英語, 研究発表ペーパー・要旨（国際会議）, 0168-0102, WOS:000261548101403 - 223. 両手同時ポインティング動作中の眼球運動制御(神経・感覚)
國部 雅大; 安藤 創一; 小田 伸午
日本体力医学会, 出版日 2003年12月01日, 体力科學, 52巻, 6号, 掲載ページ 826-826, 日本語, 0039-906X, 110001913766, AN00137986 - 球技経験がキー押しおよびサッケード眼球運動による周辺視野反応時間に及ぼす影響
国部雅大; 安藤創一; 来田宣幸; 小田伸午
出版日 2002年12月01日, 体力科学, 51巻, 6号, 掲載ページ 559, 日本語, 0039-906X, 200902113613780352 - Attentionの大きさが中心視野と周辺視野の反応時間に与える影響
安藤創一; 国部雅大; 来田宣幸; 小田伸午
出版日 2002年12月01日, 体力科学, 51巻, 6号, 掲載ページ 803, 日本語, 0039-906X, 200902195916669256
書籍等出版物
- 健康論 大学生のためのヘルスプロモーション
分担執筆, 第７章 エイジングと健康, 道和書院, 出版日 2023年03月 - 大学生のための「健康」論
教科書・概説・概論, 日本語, 分担執筆, 第６章 スポーツと健康論, 道和書院, 出版日 2016年03月 - Exercise-Cognition Interaction
英語, 分担執筆, Chapter 6: Acute Exercise and Cognition: Effects of Cerebral Oxygenation and Blood Flow, Elsevier, 出版日 2016年01月 - エンデュランストレーニングの科学
日本語, 共訳, 第23章，27章, NAP, 出版日 2015年08月 - ランニングリテラシー
一般書・啓蒙書, 日本語, 分担執筆, 大修館書店, 出版日 2011年08月 - ヒトの動き百話
日本語, 分担執筆, 市村出版, 出版日 2011年02月 - スポーツの百科事典
事典・辞書, 日本語, 分担執筆, 丸善出版, 出版日 2007年01月 - 脳百話―動きの仕組みを解き明かす―
日本語, 分担執筆, 市村出版, 出版日 2003年10月 - ヒトの動きの神経科学
日本語, 共訳, 市村出版, 出版日 2002年04月
講演・口頭発表等
- 豊かな環境によるヒラメ筋の肥大と脳機能との関係性
須藤みず紀; 狩野豊; 安藤創一
第78回日本体力医学会, 査読付
発表日 2024年09月03日
開催期間 2024年09月02日- 2024年09月04日 - 一過性の運動による脳内ドーパミンの遊離と認知パフォーマンス
安藤創一; 藤本敏彦; 須藤みず紀; 田代学
シンポジウム・ワークショップパネル（公募）, 第78回日本体力医学会, 招待, 査読付
発表日 2024年09月02日
開催期間 2024年09月02日- 2024年09月04日 - 骨格筋への電気刺激に対する順応時の生理的応答
寺田紘基; 二宮渉; 加納康裕; 須藤みず紀; 安藤創一
第32回日本運動生理学会, 査読付
発表日 2024年08月23日
開催期間 2024年08月22日- 2024年08月23日 - 骨格筋への電気刺激を用いた研究の新展開
安藤創一; 須藤みず紀
公開講演，セミナー，チュートリアル，講習，講義等, 第32回日本運動生理学会, 招待, 査読付
発表日 2024年08月23日
開催期間 2024年08月22日- 2024年08月23日 - 高齢者における大腿筋横断面積および筋内脂肪の経年変化
加納康裕; 安藤創一; 冨賀理恵; 須藤みず紀; 古瀬裕次郎; 檜垣靖樹; 田中宏暁; 畑本陽一
第32回日本運動生理学会, 査読付
発表日 2024年08月23日
開催期間 2024年08月22日- 2024年08月23日 - 豊かな環境における自発性身体活動量と海馬における発現変動遺伝子の関係
須藤 みず紀; 竹田 怜央; 草野達哉; 星野太佑; 安藤創一; 狩野豊
第32回日本運動生理学会, 査読付
発表日 2024年08月23日
開催期間 2024年08月22日- 2024年08月23日 - 脳血流から認知課題中の神経活動を定量化する方法の検討
二宮渉; 安藤創一; 斎藤 祥太郎; 國松なる実; 小河繁彦
第32回日本運動生理学会, 査読付
発表日 2024年08月22日
開催期間 2024年08月22日- 2024年08月23日 - Effects of electrical muscle stimulation and resistance exercise training on muscle strength and hypertrophy
S. Ando; Y. Hashimoto; I. Kanno; K. Kano; K. Anjiki; M. Ogawa; M. Fujibayashi; M. Sudo; T. Okamoto
29th Annual Congress of the European College of Sport Science, 査読付
発表日 2024年07月05日
開催期間 2024年07月02日- 2024年07月05日 - Physical activity reduces stress hormone level and anxiety-like behaviors in environmental enrichment
M Sudo; S. Ando
29th Annual Congress of the European College of Sport Science, 査読付
発表日 2024年07月05日
開催期間 2024年07月02日- 2024年07月05日 - Brain volume and muscle mass reductions were not prevented by once-a-week exercise in the older people
S. Ando; R. Tomiga; M. Sudo; K. Anjiki; K. Kano; Y. Kose; Y. Higaki; H. Tanaka; Y. Hatamoto
American College of Sports Medicine 71th Annual Meeting, 査読付
発表日 2024年05月27日
開催期間 2024年05月27日- 2024年05月30日 - Doubly labelled water-measured physical activity level is associated with brain volume and cognitive function, but not with muscle size in the elderly
M. Sudo; R. Tomiga; K. Anjiki; K. Kano; Y. Kose; Y. Yamada; N. Ebine; Y. Higaki; H. Tanaka; S. Ando; Y. Hatamoto
American College of Sports Medicine 71th Annual Meeting, 査読付
発表日 2024年05月27日
開催期間 2024年05月27日- 2024年05月30日 - 骨格筋への電気刺激と抵抗性運動のトレーニングによる筋肥大の特性
菅野樹; 橋本佑斗; 安喰康太; 加納康裕; 小川まどか; 藤林真美; 須藤みず紀; 岡本孝信; 安藤創一
第36回日本トレーニング科学会, 査読付
発表日 2023年10月 - 骨格筋への電気刺激が認知パフォーマンスに及ぼす影響
寺田紘基; 橋本佑斗; 安喰康太; 加納康裕; 菅野樹; 小川まどか; 藤林真美; 須藤みず紀; 岡本孝信; 安藤創一
第36回日本トレーニング科学会, 査読付
発表日 2023年10月 - 膝関節伸展筋群を対象とした8週間の神経骨格筋電気刺激トレーニングが筋力および筋体積に及ぼす影響
山田恒輝; 御代川雄祐; 塩崎大悟; 矢島祥成; 加納康裕; 橋本佑斗; 岡本孝信; 安藤創一; 赤木亮太
第36回日本トレーニング科学会, 査読付
発表日 2023年10月 - 下肢骨格筋電気刺激トレーニングは血管内皮機能と動脈スティフネスを改善する
橋本佑斗; 安藤創一; 岡本孝信
日本体育・スポーツ・健康学会第73回大会, 査読付
発表日 2023年08月 - Effects of physical activity level and motor function on hippocampal volume in the older adults
K. Anjiki; S. Ando; R. Tomiga; K. Ishimura; Y. Kose; K. Kano; M. Sudo; Y. Yamada; N. Ebine; Y. Higaki; H. Tanaka; Y. Hatamoto
29th Congress of the International Society of Biomechanics, 査読付
発表日 2023年07月 - Characteristic of thigh muscle hypertrophy induced by electrical muscle stimulation training
K. Kano; R. Akagi; Y. Hashimoto; Y. Miyokawa; D. Shiozaki; Y. Yajima; K. Yamada; S. Kanbayashi; K. Anjiki; I. Kanno; M. Sudo; T. Okamoto; S Ando
29th Congress of the International Society of Biomechanics, 査読付
発表日 2023年07月 - Effects of physical activity level on quadriceps femoris muscle and intramuscular adipose tissue in the elderly
K. Anjiki; S. Ando; R. Tomiga; Y. Kose; S. Fukuoka; M. Sudo; Y. Yamada; N. Ebine; Y. Higaki; H. Tanaka; Y. Hatamoto
28th Annual Congress of the European College of Sport Science, 査読付
発表日 2023年07月 - K. Kano, Y. Ishioka, S. Kanbayashi, JT. Costello, M Sudo, S. Ando.
Combined effects of electrical muscle stimulation; cycling exercise on cognitive; fo; mance
28th Annual Congress of the European College of Sport Science, 査読付
発表日 2023年07月 - Effects of different environmental enrichment on spontaneous physical activity and spatial learning
M. Sudo; S. Ando
28th Annual Congress of the European College of Sport Science, 査読付
発表日 2023年07月 - Effect of electrical muscle stimulation training on arterial function in healthy young men
Y. Hashimoto; S. Kanbayashi; K. Anjiki; I. Kanno; K. Kano; Y. Miyokawa; D. Shiozaki; Y. Yajima; K. Yamada; M. Sudo; R. Akagi; S. Ando; T. Okamoto
28th Annual Congress of the European College of Sport Science, 査読付
発表日 2023年07月 - Influence of (in)congruent visual information on thermal perception during exercise in the heat: a randomised controlled crossover trial
H. Mayes; M. Navarro; L. Satchell; D. Mueller; J. Badariotti; D. White; M. Tipton; S. Ando; JT. Costello
28th Annual Congress of the European College of Sport Science, 査読付
発表日 2023年07月 - The Isolated and Combined Effects of Acute Hypoxia, Overnight Sleep Deprivation, and Exercise on Cognitive and Physiological Function
TB. Williams; J. Corbe; MJ. Tipton; T. McMorris; JI. Badariotti; HS. Mayes; DK. White; AJ. Causer; FA. Carvalho; MO. Parker; R. Thelwell; S. Ando; JT. Costello
28th Annual Congress of the European College of Sport Science, 査読付
発表日 2023年07月 - JI. Badariotti,,HS. Mayes, M. Miller-Dicks, TB. Williams, MO. Parker, S. Ando, JT. Costello.
The Individual; Combined Effects of Exercise; Three Consecutive; Nights of Partial Sleep Deprivation on; Executive Functions
28th Annual Congress of the European College of Sport Science, 査読付
発表日 2023年07月 - S. Ando, Y. Hashimoto, T. Asamizu, R. Sato, S. Kanbayashi, K. Kano, M. Ogawa, M. Fujibayashi, M. Sudo, T. Okamoto.
The effects of electrical muscle stimulation; raining on; quadriceps muscle strength and hypertrophy, mood states
American College of Sports Medicine 70th Annual Meeting, 査読付
発表日 2023年05月 - Does spontaneous physical activity level determine cognitive benefits from the environmental enrichment?
M. Sudo; Y. Kano; S. Ando
American College of Sports Medicine 70th Annual Meeting, 査読付
発表日 2023年05月 - 異なる豊かな環境条件が不安様行動の応答時間と後肢筋に及ぼす影響
須藤みず紀; 狩野豊; 安藤創一
日本生理学会第100回記念大会, 査読付
発表日 2023年03月 - 一過性有酸素運動による認知パフォーマンス向上と機能的結合との関係
石村建人; 片桐悠貴; 水口暢章; 望月航大; 篠田理人; 須藤みず紀; 大河原一憲; 妹尾淳史; 安藤創一
ポスター発表, 日本語, 第77回日本体力医学会
発表日 2022年09月23日 - 電気刺激と自転車運動の組み合わせが認知パフォーマンスにもたらす効果
上林紗梨; 石岡優花; 須藤みず紀; 安藤創一
ポスター発表, 日本語, 第77回日本体力医学会
発表日 2022年09月23日 - 急性疲労に伴う指尖動脈脈波指数の変化：ユース女子サッカー選手での検討
菅原順; 小河菜々; 渡邊裕宣; 齋藤祥太郎; 安藤創一; 大須賀まき; 長谷川哲矢; 小河繁彦
ポスター発表, 日本語, 第77回日本体力医学会
発表日 2022年09月22日 - 朝食欠食がもたらす昼食後高血糖の認知機能に対する負の効果
塚本敏人; 道羅絢斗; 杉本岳史; 鈴木飛鳥; 石橋彩; 安藤創一; 水口暢章; 橋本健志
ポスター発表, 日本語, 第77回日本体力医学会
発表日 2022年09月22日 - 一過性の運動による白質及び灰白質の拡散の変化
篠田理人; 片桐悠貴; 水口暢章; 望月航大; 須藤みず紀; 大河原一憲; 妹尾淳史; 安藤創一
ポスター発表, 日本語, 第77回日本体力医学会
発表日 2022年09月22日 - 豊かな環境条件の違いは情動における行動パターンの応答時間に影響する
須藤みず紀; 須藤惇; 安藤創一
ポスター発表, 日本語, 第77回日本体力医学会
発表日 2022年09月22日 - 骨格筋への電気刺激トレーニングが血管内皮機能と認知パフォーマンスへ及ぼす影響
佐藤瑠唯,橋本佑斗,浅水太郎,上林紗梨,小川まどか,須藤みず紀,岡本孝信,安藤創一,藤林真美
ポスター発表, 日本語, 第77回日本体力医学会, 査読付
発表日 2022年09月21日
開催期間 2022年09月21日 - 格筋への電気刺激トレーニングが血管内皮機能と認知パフォーマンスへ及ぼす影響
佐藤瑠唯; 橋本佑斗; 浅水太郎; 上林紗梨; 小川まどか; 須藤みず紀; 岡本孝信; 安藤創一; 藤林真美
ポスター発表, 日本語, 第77回日本体力医学会
発表日 2022年09月21日 - 骨格筋への電気刺激トレーニングが筋力および筋肥大へ及ぼす影響
浅水太郎; 橋本佑斗; 佐藤瑠唯; 上林紗梨; 小川まどか; 須藤みず紀; 岡本孝信; 安藤創一; 藤林真美
ポスター発表, 日本語, 第77回日本体力医学会
発表日 2022年09月21日 - 低酸素環境での運動による認知パフォーマンスの変化とその低下の予防法
安藤創一
シンポジウム・ワークショップパネル（公募）, 日本語, 第77回日本体力医学会
発表日 2022年09月21日 - 酸素濃度と低酸素暴露時間の様々な組み合わせが骨格筋への酸素供給能へ及ぼす影響について
高倉久志; 大澤晴太; 見目大悟; 須藤みず紀; 安藤創一; 井澤鉄也
口頭発表（一般）, 日本語, 第30回日本運動生理学会
発表日 2022年08月26日 - 豊かな環境における自発的な身体活動が後肢筋の各部位に与える影響
須藤みず紀; 安藤創一
口頭発表（一般）, 日本語, 第30回日本運動生理学会
発表日 2022年08月26日 - 骨格筋への電気刺激が自律神経に及ぼす影響：随意運動との比較
安藤創一; 須藤みず紀
口頭発表（一般）, 日本語, 第30回日本運動生理学会
発表日 2022年08月26日 - The Effects Of Environmental Enrichment In The Absence Of Wheel Exercise On Locomotion Activity And Anxiety-like Behavior.
Sudo M; Kano Y; Ando S
ポスター発表, 英語, American College of Sports Medicine 69th Annual Meeting
発表日 2022年05月31日 - Effects Of Electrical Muscle Stimulation On Cognition, Autonomic Nervous System Activity, And Mood States
Ando S; Takagi Y; Mochizuki K; Kitajima D; Fujibayashi M; Tsurugano S; Sudo M
ポスター発表, 英語, American College of Sports Medicine 69th Annual Meeting
発表日 2022年05月31日 - 豊かな環境における走行運動の有無が身体活動量・骨格筋・情動に及ぼす影響
須藤みず紀; 安藤創一; 狩野豊
口頭発表（一般）, 日本語, 第76回日本体力医学会
発表日 2021年09月17日 - 低酸素暴露が脳および末梢血管内皮機能に及ぼす影響
小河繁彦; 鷲尾拓郎; 塚本敏人; 安藤創一; 橋本健志; Damian M. Bailey
口頭発表（一般）, 日本語, 第76回日本体力医学会
発表日 2021年09月17日 - 筆記動作における手部および前腕部の筋活動評価
松浦広季; 安藤創一; 今野大成; YuChen Lin; 伊藤浩; 根本彩香; 久保均; 田代学
口頭発表（一般）, 日本語, 第76回日本体力医学会
発表日 2021年09月17日 - 骨格筋への電気刺激と随意運動の組み合わせは認知パフォーマンスを向上させる
安藤創一; 高木瑶子; 望月航大; 北島大輔; 片桐悠貴; 宗平麗; 松浦広季; 藤林真美; 鶴ケ野しのぶ; 佐藤耕平; 須藤みず紀
口頭発表（一般）, 日本語, 第76回日本体力医学会
発表日 2021年09月17日 - 大脳基底核の構造が安静時及び運動中の認知パフォーマンスを予測するか？
片桐悠貴; 妹尾淳史; 水口暢章; 須藤みず紀; 大河原一憲; 鶴ヶ野しのぶ; 安藤創一
口頭発表（一般）, 日本語, 第76回日本体力医学会
発表日 2021年09月17日 - 運動による認知パフォーマンスの向上：ドーパミンの関与
安藤創一; 藤本敏彦; 田代学
シンポジウム・ワークショップパネル（公募）, 日本語, 第76回日本体力医学会, 招待, 国内会議
発表日 2021年09月17日 - Effects of Acute Stretching on Cognitive Function and Mood States of Physically Inactive Young Adults
Sudo M; Ando S
ポスター発表, 英語, 26th Annual Congress of the European College of Sport Science, 国際会議
発表日 2021年09月08日 - Combined effects of electrical muscle stimulation and arm cranking on cognitive performance
Matsuura K; Ando S; Takagi Y; Mochizuki K; Kitajima D; Katagiri Y; Munehira U; Fujibayashi M; Costello JT; Tsurugano S; Sato K; Sudo M
ポスター発表, 英語, 26th Annual Congress of the European College of Sport Science
発表日 2021年09月08日 - 豊かな飼育環境がラットの身体活動量・脳由来神経栄養因子・情動に及ぼす影響
須藤みず紀; 池上諒; 狩野豊; 安藤創一
口頭発表（一般）, 日本語, 第29回日本運動生理学会
発表日 2021年08月21日 - 運動と認知機能を支える基盤
安藤創一
シンポジウム・ワークショップパネル（公募）, 日本語, 第29回日本運動生理学会, 招待, 国内会議
発表日 2021年08月20日 - Effects of acute exercise and hypoxia on cognitive performance.
Ando S
口頭発表（招待・特別）, 英語, 25th Annual Congress of the European College of Sport Science, 招待
発表日 2020年10月30日 - Evaluation of small and deep muscle activities during handwriting using 18F-FDG positron emission tomography.
Matsuura K; Ando S; Konno T; Lin Y; Takeda K; Kuo L; Nemotor A; Ito H; Kubo H; Tashiro M
ポスター発表, 英語, 25th Annual Congress of the European College of Sport Science
発表日 2020年10月28日 - Does structure of the brain predict cognitive performance at rest and during exercise?
Katagiri Y; Senoo A; Mizuguchi N; Tamura T; Saito S; Wang S; Mochizuki K; Sudo M; Ohkawara K; Tsurugano S; Ando S
ポスター発表, 英語, 25th Annual Congress of the European College of Sport Science
発表日 2020年10月28日 - Differential effects of electrical muscle stimulation and voluntary exercise on cognitive performance: role of sympathetic nervous system activation.
Mochizuki K; Takagi Y; Kitajima D; Katagiri Y; Sudo M; Fujibayashi M; Tsurugano S; Ando S
ポスター発表, 英語, 25th Annual Congress of the European College of Sport Science
発表日 2020年10月28日 - 持久的運動後に短時間低酸素曝露を行うトレーニングプロトコルが骨格筋有酸素性代謝能力に及ぼす影響について
高倉久志; 高橋和也; 須藤みず紀; 安藤創一; 加藤久詞; 大澤晴太; 井澤鉄也
ポスター発表, 日本語, 第75回日本体力医学会大会
発表日 2020年09月26日 - 把握運動による認知機能亢進は運動様式に影響を受けるか？
齋藤祥太郎; 鷲尾拓郎; 渡邊裕宣; 田宮一樹; 山田朋照; 安藤創一; 小河繁彦
ポスター発表, 日本語, 第75回日本体力医学会大会
発表日 2020年09月25日 - Effect of Intermittent Isometric Handgrip Exercise On Cognitive Function.
Saito S; Tamiya K; Washio T; Watanabe H; Ando S; Ogoh S
ポスター発表, 英語, American College of Sports Medicine 67th Annual Meeting
発表日 2020年05月28日 - The effects of acute isometric handgrip exercise on cognitive function
Takuro Washio; Kazuya Suzuki; Shotaro Saito; Kazuki Tamiya; Hironori Watanabe; Soichi Ando; Shigehiko Ogoh
ポスター発表, 英語, The 97th Annual Meeting of the Physiological Society of Japan
発表日 2020年03月19日 - Differences in Sympathetic nervous system activity between electrical muscle stimulation and voluntary exercise
Kitajima D; Takagi Y; Sudo M; Fujibayashi M; Tsurugano S; Ando S
ポスター発表, 英語, The Irago Conference
発表日 2019年10月29日 - Acute exercise induces increased arousal level and improves cognitive performance
Wang S; Senoo A; Saito S; Sudo M; Ohkawara K; Ando S
ポスター発表, 英語, The Irago Conference
発表日 2019年10月29日 - Evaluation of Muscle Activity During Writing and Tapping Movements by Using Surface Electromyogram
Matsuura K; Konno T; Ando S
ポスター発表, 英語, The Irago Conference
発表日 2019年10月29日 - Mood changes induced by Electrical Muscle Stimulation and voluntary exercise
Mochizuki K; Kitajima D; Takagi Y; Sudo M; Tsurugano S; Fujibayashi M; Ando S
ポスター発表, 英語, The Irago Conference
発表日 2019年10月29日 - Does volume of basal ganglia predict cognitive performance at rest and during exercise?
Katagiri Y; Senoo A; Tamura T; Wang S; Mizuguchi N; Sudo M; Ohkawara K; Ando S
ポスター発表, 英語, The Irago Conference
発表日 2019年10月29日 - 運動と認知の二重課題開始時の呼吸循環応答
石田浩司; 張魯玉; 須藤みず紀; 安藤創一; 片山敬章
口頭発表（一般）, 日本語, 第74回日本体力医学会
発表日 2019年09月21日 - 異なる条件における豊かな環境暴露による身体活動量と不安様感情の関係性
須藤みず紀; 安藤創一
ポスター発表, 日本語, 第74回日本体力医学会, 国内会議
発表日 2019年09月21日 - 筆記およびタッピング動作時の筋活動評価
今野大成; 安藤創一; Yuchen Lin; 伊藤浩; 久保均; 田代学
ポスター発表, 日本語, 第74回日本体力医学会
発表日 2019年09月21日 - 運動による脳内ドーパミンと神経活動の変化：認知パフォーマンスの変化
安藤創一
シンポジウム・ワークショップパネル（公募）, 日本語, 第74回日本体力医学会
発表日 2019年09月20日 - 一過性運動後の短時間低酸素暴露が骨格筋有酸素性代謝能力に及ぼす影響について
高倉久志; 渡邊大和; 須藤みず紀; 安藤創一; 加藤久詞; 大澤晴太; 井澤鉄也
ポスター発表, 日本語, 第74回日本体力医学会
発表日 2019年09月19日 - 認知課題の違いが二重課題のパフォーマンスに及ぼす影響
張魯玉; 須藤みず紀; 安藤創一; 片山敬章; 石田浩司
口頭発表（一般）, 日本語, 第74回日本体力医学会
発表日 2019年09月19日 - 一過性の運動による認知パフォーマンスと機能的結合の変化
齋藤颯太; 妹尾淳史; Wang Shan; 水口暢章; 須藤みず紀; 大河原一憲; 安藤創一
口頭発表（一般）, 日本語, 第74回日本体力医学会
発表日 2019年09月19日 - 一過性の運動による認知パフォーマンスの向上に対する内因性ドーパミンの関与
安藤創一; 藤本敏彦; 四月朔日聖一; Fairuz Nasir; 平岡宏太良; 武田和子; 小林中; 今野大成; Yuchen Lin; 渡部浩司; 田代学
口頭発表（一般）, 日本語, 第74回日本体力医学会
発表日 2019年09月19日 - Sympathetic nervous system activity during electrical muscle stimulation and voluntary exercise.
Kitajima D; Takagi Y; Sudo M; Fujibayashi M; Tsurugano S; Ando S
ポスター発表, 英語, 1st International Sport Neuroscience Conference (IBRO Satellite Forum), 国際会議
発表日 2019年09月18日 - Effects of electrical muscle stimulation on cognitive performance and cerebral blood flow
Takagi Y; Sato K; Kitajima D; Koike Y; Watanabe H; Sudo M; Fujibayashi M; Tsurugano M; Ando S
ポスター発表, 英語, 1st International Sport Neuroscience Conference (IBRO Satellite Forum), 国際会議
発表日 2019年09月18日 - Cognitive performance is associated with cerebral oxygenation and peripheral oxygen saturation, but not plasma catecholamines, during graded normobaric hypoxia
Williams TB; Corbett J; McMorris T; Young JS; Dicks M; Ando S; Thelwell RC; Tipton MJ; Costello JT
口頭発表（一般）, 英語, International Conference on Environmental Ergonomics
発表日 2019年07月12日 - The importance of breakfast glycemic control on systemic BDNF and dynamic cerebral autoregulation in men.
Tsukamoto H; Ishibashi A; Marley CJ; Shinohara Y; Ando S; Bailey DM; Hashimoto T; Ogoh S
ポスター発表, 英語, Physiology 2019
発表日 2019年07月09日 - Spontaneous locomotor activity reduces anxiety-like behavior in environmental enrichment
Sudo M; Ando S
ポスター発表, 英語, 24th Annual Congress of the European College of Sport Science, 国際会議
発表日 2019年07月06日 - Effect of different cognitive tasks on dual-task performance
Zhang L; Sudo M; Ando S; Katayama K; Ishida, K
ポスター発表, 英語, 24th Annual Congress of the European College of Sport Science, 国際会議
発表日 2019年07月05日 - Effects of electrical muscle stimulation on cognitive performance and cerebral perfusion
Takagi Y; Sato K; Koike Y; Watanabe H; Sudo M; Fujibayashi M; Tsurugano S; Ando S
ポスター発表, 英語, 24th Annual Congress of the European College of Sport Science, 国際会議
発表日 2019年07月05日 - Effects of alterations in visual flow on physiological and psychological responses to exercise
Ando S; Yasukawa K; Koike Y; Konno T; Sudo M; Ohkawara K
ポスター発表, 英語, 24th Annual Congress of the European College of Sport Science, 国際会議
発表日 2019年07月04日 - Effects of video viewing not aimed at motivating exercise during ergometer exercise on voluntary exercise duration
Shimizu S; Nagashima M; Okada K; Suzuki M; Ando S; Ohkawara K
ポスター発表, 英語, 24th Annual Congress of the European College of Sport Science, 国際会議
発表日 2019年07月03日 - Alterations in functional connectivity is associated with cognitive improvement induced by acute exercise
Saito S; Senoo A; Wang S; Mizuguchi N; Sudo M; Ohkawara K; Ando S
ポスター発表, 英語, 24th Annual Congress of the European College of Sport Science, 国際会議
発表日 2019年07月03日 - Association between endogenous dopamine release and cognitive improvement during exercise
Konno T; Tashiro M; Fujimoto T; Watanuki S; Nasir BMF; Hiraoka K; Kobayashi A; Lin Y; Watabe H; Ando S
ポスター発表, 英語, 24th Annual Congress of the European College of Sport Science
発表日 2019年07月03日 - Effect of isometric handgrip exercise on hypercapnia-induced shear-mediated dilation in the internal carotid artery.
Washio T; Suzuki K; Yamagata T; Ando S; Ogoh S
ポスター発表, 英語, American College of Sports Medicine 66th Annual Meeting, 国際会議
発表日 2019年05月31日 - Environmental enrichment increases spontaneous locomotor activity in rats.
Sudo M; Ando S
ポスター発表, 英語, American College of Sports Medicine 66th Annual Meeting
発表日 2019年05月30日 - Acute exercise alters functional connectivity during cognitive task.
Ando S; Saito S; Mizuguchi N; Sudo M; Ohkawara K; Senoo A
ポスター発表, 英語, American College of Sports Medicine 66th Annual Meeting
発表日 2019年05月29日 - 運動の有能性に着目したサポートが運動教室中の身体活動量に及ぼす影響
山﨑直輝; 瀑布川竜次; 坂本一憲; 安藤創一; 鶴ヶ野しのぶ; 大河原一憲
ポスター発表, 日本語, 日本健康支援学会, 国内会議
発表日 2019年03月 - 運動意欲の促進を意図しない映像視聴が運動持続時間に与える影響
永島雅章; 伊藤隆汰; 山﨑直輝; 鈴木美穂; 岡田幸樹; 清水俊平; 安藤創一; 大河原一憲
ポスター発表, 日本語, 日本健康支援学会, 国内会議
発表日 2019年03月 - 高強度運動時の脳血流の低下は認知機能の低下に関与しない
安藤創一; 小見山高明; 田上友季也; 須藤みず紀; 上原吉就; 田中宏暁; 檜垣靖樹
口頭発表（一般）, 日本語, 第73回日本体力医学会
発表日 2018年09月 - 一過性運動による認知課題中の機能的結合の変化
齋藤颯太; 妹尾淳史; 水口暢章; 須藤みず紀; 大河原一憲; 安藤創一
口頭発表（一般）, 日本語, 第73回日本体力医学会
発表日 2018年09月 - 運動中の視覚情報の変化が生理的・心理的応答に与える影響
今野大成; 安川巧樹; 小池祐太; 須藤みず紀; 大河原一憲; 安藤創一
口頭発表（一般）, 日本語, 第73回日本体力医学会
発表日 2018年09月 - ラットにおける豊かな環境飼育は自発的な身体活動量と空間認知記憶能力を増加させる
須藤みず紀; 安藤創一
口頭発表（一般）, 日本語, 第73回日本体力医学会
発表日 2018年09月 - Impaired cognitive function during intense exercise is not associated with decrease in cerebral blood flow
Ando S; Komiyama T; Tanoue Y; Sudo M; Costello J; Uehara Y; Tanaka H; Higaki Y
口頭発表（一般）, 英語, 23rd Annual Congress of the European College of Sport Science, 国際会議
発表日 2018年07月 - An enriched environment increases locomotor activity and induces skeletal muscles hypertrophy in rats.
Sudo M; Nagamatsu T; Ando S
口頭発表（一般）, 英語, 23rd Annual Congress of the European College of Sport Science, 国際会議
発表日 2018年07月 - 低酸素環境下での運動と認知機能
安藤創一
口頭発表（一般）, 日本語, 第57回日本生体医工学会大会, 国内会議
発表日 2018年06月21日 - Performance in Square Stepping Exercise is associated with working memory.
Ando S; Makino R; Takigawa R; Yasukawa K; Kokubu M; Sakamoto K; Tsurugano S; Ohkawara K
ポスター発表, 英語, American College of Sports Medicine 65th Annual Meeting, 国際会議
発表日 2018年05月 - Increased exercise activity in an enriched environment improves anxiety-like behavior and cognition.
Sudo M; Ando S; Kano Y; Nagamatsu T
ポスター発表, 英語, American College of Sports Medicine 65th Annual Meeting, 国際会議
発表日 2018年05月 - Positive effect of transient aerobic exercise on the executive function: an fMRI study.
Kobayashi A; Senoo A; Fujita G; Mizuguchi N; Kamijo T; Maruyama K; Takigawa R; Ohkawara K; Ando S
ポスター発表, 英語, The Irago Conference
発表日 2017年11月 - 自発的な運動を促す豊かな環境は不安感情様の低下と骨格筋量の増加を惹起する．
須藤みず紀; 安藤創一; 永松俊哉
口頭発表（一般）, 日本語, 日本体力医学会, 国内会議
発表日 2017年09月 - 一過性の運動が認知機能に与える影響－fMRI研究―．
安藤創一; 小林中; 藤田豪; 水口暢章; 上條貴大; 丸山響平; 瀑布川竜次; 大河原一憲; 妹尾淳史
口頭発表（一般）, 日本語, 日本体力医学会, 国内会議
発表日 2017年09月 - 低酸素環境における動脈血酸素飽和度の低下は認知機能の向上を減弱させる．
小見山高明; 片山敬章; 須藤みず紀; 石田浩司; 桧垣靖樹; 安藤創一
口頭発表（一般）, 日本語, 日本運動生理学会
発表日 2017年07月 - 豊かな環境が骨格筋と生理的ストレス応答に及ぼす影響．
須藤みず紀; 安藤創一; 永松俊哉
ポスター発表, 日本語, 日本運動生理学会, 国内会議
発表日 2017年07月 - Relationship between affective states and physiological stress after moderate and exhaustive exercise.
Sudo M; Komiyama T; Nagamatsu T; Higaki Y; Ando S
口頭発表（一般）, 英語, 22nd Annual Congress of the European College of Sport Science, 国際会議
発表日 2017年07月 - Does cerebral blood flow and oxygenation affect decline in cognitive function during exercise?
Komiyama T; Tanoue Y; Sudo M; Uehara Y; Tanaka H; Higaki Y; Ando S
ポスター発表, 英語, 22nd Annual Congress of the European College of Sport Science, 国際会議
発表日 2017年07月 - The effect of caffeine ingestion on cognitive function and cerebral perfusion.
Takagi Y; Sato K; Ohba N; Sadamoto T; Ando S
口頭発表（一般）, 英語, 22nd Annual Congress of the European College of Sport Science, 国際会議
発表日 2017年07月 - Effects of acute aerobic exercise on executive function: an fMRI study.
Kobayashi A; Senoo A; Fujita G; Mizuguchi N; Kamijo T; Maruyama K; Takigawa R; Ohkawara K; Ando S
口頭発表（一般）, 英語, 22nd Annual Congress of the European College of Sport Science, 国際会議
発表日 2017年07月 - Improvement of cognitive function by dual task exercise.
Ito R; Ando S; Takigawa R; Sakamoto K; Kobayashi A; Tsurugano S; Tanaka K; Ohkawara K
ポスター発表, 英語, American College of Sports Medicine 64th Annual Meeting, 国際会議
発表日 2017年06月 - Effects of aerobic and resistance exercise on cognitive function.
Komiyama T; Ando K; Sudo M; Takigawa R; Ohkawara K; Uehara Y; Tanaka H; Higaki Y; Ando S
ポスター発表, 英語, American College of Sports Medicine 64th Annual Meeting, 国際会議
発表日 2017年06月 - Cognitive function after exhaustive exercise: effects of cerebral oxygenation.
Ando S; Sudo M; Komiyama T; Aoyagi R; Higaki Y
ポスター発表, 英語, American College of Sports Medicine 64th Annual Meeting, 国際会議
発表日 2017年06月 - Comparing the effects of intrinsic and extrinsic motivational support on physical activity level during exercise.
Yamazaki N; Sakamoto K; Ando S; Takigawa R; Kobayashi A; Tsurugano S; Tanaka K; Ohkawara K
ポスター発表, 英語, American College of Sports Medicine 64th Annual Meeting, 国際会議
発表日 2017年05月 - Variation in daily physical activity during an exercise intervention period in older adult Japanese.
Takigawa R; Sakamoto K; Ando S; Yamazaki N; Kobayashi A; Tsurugano S; Tanaka K; Ohkawara K
ポスター発表, 英語, American College of Sports Medicine 64th Annual Meeting, 国際会議
発表日 2017年05月 - Acute stretching improves affective states and cognitive function in physically inactive people.
Sudo M; Ando S; Tomiga Y; Nagamatsu T
ポスター発表, 英語, American College of Sports Medicine 64th Annual Meeting, 国際会議
発表日 2017年05月 - Cognitive function during exercise under hypoxia
Ando S
口頭発表（招待・特別）, 英語, 94th Annual Meeting of the Physiological Society of Japan, 招待
発表日 2017年03月29日 - The effects of downhill running training on skeletal muscle and hippocampal BDNF expression in type II diabetic rat.
Sudo M; Ando S; Tomiga Y; Nagamatsu T; Kano Y; Higaki Y
ポスター発表, 英語, The 94th Annual Meeting of the Physiological Society of Japan
発表日 2017年03月28日 - 運動プログラム参加中の高齢者における平日と休日の身体活動量―有職者と非有職者との比較検討―．
山崎直輝; 瀑布川竜次; 坂本一憲; 安藤創一; 小林中; 鶴ヶ野しのぶ; 大河原一憲
口頭発表（一般）, 日本語, 日本健康支援学会, 国内会議
発表日 2017年03月 - The effects of acute exercise on cognitive function
安藤創一
口頭発表（招待・特別）, 英語, ライフエンジニアリング部門シンポジウム, 招待
発表日 2016年11月03日 - 高脂肪食摂取及び運動介入が骨格筋nNOS発現とDNAメチル化に及ぼす影響．
冨賀裕貴; 吉村咲紀; 伊藤愛; 須藤みず紀; 安藤創一; 江島弘晃; 田中宏暁; 桧垣靖樹
口頭発表（一般）, 日本語, 日本体力医学会
発表日 2016年09月 - 身体不活動者への一過性ストレッチ運動はメンタルヘルスと認知機能を向上させる．
須藤みず紀; 安藤創一; 冨賀裕貴; 永松俊哉
口頭発表（一般）, 日本語, 日本体力医学会
発表日 2016年09月 - 一過性運動と認知機能
安藤創一
口頭発表（招待・特別）, 日本語, 第24回日本運動生理学会, 招待, 国内会議
発表日 2016年07月23日 - 2型糖尿病ラットにおけるダウンヒルトレーニングが海馬のBDNF産生に及ぼす影響．
須藤みず紀; 安藤創一; 冨賀裕貴; 永松俊哉; 田中宏暁; 桧垣靖樹
ポスター発表, 日本語, 日本運動生理学会
発表日 2016年07月 - Reduction In Oxygen Delivery Under Severe Hypoxia Affects Cognitive Function During Moderate Exercise
Komiyama T; Katayama K; Sudo M; Ishida K; Higaki Y; Ando S
ポスター発表, 英語, American College of Sports Medicine, 国際会議
発表日 2016年06月 - Cognitive function and affective states following exercise under severe hypoxia.
Sudo M; Komiyama T; Nagamatsu T; Higaki Y; Ishida K; Katayama K; Ando S
ポスター発表, 英語, American College of Sports Medicine, 国際会議
発表日 2016年06月 - Association between anxiety-like behavior and neuronal nitric oxide synthase in old mice under enriched environment.
Tomiga Y; Ito A; Maruyama A; Sudo M; Ando S; Kawanaka K; Tanaka H; Higaki Y
ポスター発表, 英語, American College of Sports Medicine
発表日 2016年06月 - 異なる糖質濃度の溶液でのマウスリンスが持久的運動能力に及ぼす影響．
橋本直之; 鬼塚純玲; 石川亮; 安藤創一; 長谷川博
口頭発表（一般）, 日本語, 日本体力医学会, 国内会議
発表日 2015年09月 - 片脚ギプス固定による筋萎縮がnNOSプロモーター領域のDNAメチル化修飾に及ぼす影響．
冨賀裕貴; 伊藤愛; 須藤みず紀; 安藤創一; 中島志穂子; 田中宏暁; 檜垣靖樹
ポスター発表, 日本語, 日本体力医学会, 国内会議
発表日 2015年09月 - 組織及び筋線維タイプにおけるnNOSのDNAメチル化修飾に関する研究．
伊藤愛; 冨賀裕貴; 須藤みず紀; 安藤創一; 中島志穂子; 田中宏暁; 檜垣靖樹
ポスター発表, 日本語, 日本体力医学会, 国内会議
発表日 2015年09月 - ICP-MSによる細胞内外液測定の妥当性．
山田陽介; 走井裕香子; 安藤創一; 糸井亜弥; 吉川豊; 安井裕之; 森本武利; 木村みさか
口頭発表（一般）, 日本語, 日本体力医学会, 国内会議
発表日 2015年09月 - 朝食欠食後でも運動は認知機能を向上させるか？
小見山高明; 安藤創一; 須藤みず紀; 清永明; 田中宏暁; 桧垣靖樹
口頭発表（一般）, 日本語, 日本体力医学会, 国内会議
発表日 2015年09月 - 一過性のストレッチ運動による心理的変化が認知課題のパフォーマンスに及ぼす影響
須藤みず紀; 安藤創一; 泉水宏臣; 永松俊哉
ポスター発表, 日本語, 日本体力医学会, 国内会議
発表日 2015年09月 - 1回の運動が感情状態に及ぼす効果はどこまで続くのか？
安藤創一; 小見山高明; 青柳遼; 畑本陽一; 須藤みず紀; 檜垣靖樹
ポスター発表, 日本語, 日本体力医学会, 国内会議
発表日 2015年09月 - Moderate exercise improves cognitive function even under severe hypoxia.
Komiyama T; Katayama K; Ito Y; Sudo M; Ishida K; Higaki Y; Ando S
口頭発表（一般）, 英語, European College of Sport Science, 国際会議
発表日 2015年06月 - 一過性の運動が認知機能に及ぼす影響
安藤創一
口頭発表（招待・特別）, 日本語, 第19回日本体力医学会 東海地方会学術集会, 招待, 国内会議
発表日 2015年03月07日 - The effects of acute exercise and hypoxia on cognitive function
Ando S; Komiyama T; Sudo M; Higaki Y
シンポジウム・ワークショップパネル（公募）, 英語, 17th World Congress of Psychophysiology, 招待, 国際会議
発表日 2014年09月24日 - 低酸素環境下での運動中の認知機能
安藤創一
シンポジウム・ワークショップパネル（公募）, 日本語, 第69回日本体力医学会, 招待, 国内会議
発表日 2014年09月19日 - The effect of intense exercise on cognitive function.
Komiyama T; Ando S; Hatamoto Y; Sudo M; Kiyonaga A; Tanaka H; Higaki Y
口頭発表（一般）, 英語, 17th World Congress of Psychophysiology, 国際会議
発表日 2014年09月 - 高強度の運動中にみられる周辺視野での反応の遅延は知覚能力の低下である．
安藤創一; 小見山高明; 國部雅大; 須藤みず紀; 清永明; 田中宏暁; 桧垣靖樹
口頭発表（一般）, 日本語, 日本体力医学会
発表日 2014年09月 - 高強度運動が認知機能に及ぼす影響
小見山高明; 安藤創一; 畑本陽一; 須藤みず紀; 清永 明; 田中宏暁; 桧垣靖樹
口頭発表（一般）, 日本語, 日本体力医学会
発表日 2014年09月 - 疲労困憊運動による心理的・生理的作用が認知機能に及ぼす影響
須藤みず紀; 小見山高明; 青柳遼; 桧垣靖樹; 永松俊哉; 安藤創一
ポスター発表, 日本語, 日本体力医学会
発表日 2014年09月 - 運動中に周りは見えなくなるのか？－スポーツ科学からのアプローチ―
安藤創一
シンポジウム・ワークショップパネル（公募）, 日本語, 第24回体力・栄養・免疫学会大会, 招待, 国内会議
発表日 2014年08月30日 - Is peripheral visual perception vulnerable to strenuous exercise?
Ando S; Komiyama T; Kagimoto T; Kokubu M; Sudo M; Kiyonaga A; Tanaka H; Higaki Y
口頭発表（一般）, 英語, 19th Annual Congress of the European College of Sport Science, 国際会議
発表日 2014年07月 - Effect of acute exercise under moderate hypoxia on cognitive function.
Komiyama T; Ando S; Sudo M; Okuda N; Kiyonaga A; Tanaka H; Higaki Y
ポスター発表, 英語, 19th Annual Congress of the European College of Sport Science
発表日 2014年07月 - Cognitive function immediately after maximal exercise.
Sudo M; Komiyama T; Aoyagi R; Higaki Y; Nagamatsu T; Ando S
口頭発表（一般）, 英語, 19th Annual Congress of the European College of Sport Science
発表日 2014年07月
担当経験のある科目_授業
所属学協会
共同研究・競争的資金等の研究課題
- 骨格筋量の維持に資するたんぱく質必要量と食習慣の解明
畑本 陽一; 松本 麻衣; 佐藤 俊太朗; 田中 茂穂; 上原 吉就; 北嶋 康雄; 安藤 創一; 濱田 有香; 吉村 英一; 高田 和子; 川中 健太郎
日本学術振興会, 科学研究費助成事業, 国立研究開発法人医薬基盤・健康・栄養研究所, 基盤研究(B), 23K25615
研究期間 2023年04月01日 - 2027年03月31日 - 骨格筋振動刺激はストレスから脳機能を守れるか？間質液に着目した新たな予防法の確立
須藤 みず紀; 高倉 久志; 安藤 創一; 狩野 豊
日本学術振興会, 科学研究費助成事業, 公益財団法人明治安田厚生事業団体力医学研究所, 基盤研究(B), 22H03477
研究期間 2022年04月01日 - 2026年03月31日 - 認知機能に有益な運動の本質とは？電気刺激併用による検証と新たな運動処方の確立
安藤 創一; 藤本 敏彦; 田代 学; 橋本 佑斗; 須藤 みず紀; 岡本 孝信; 樽味 孝
日本学術振興会, 科学研究費助成事業, 電気通信大学, 基盤研究(B), 22H03493
研究期間 2022年04月 - 2026年03月 - 骨格筋への電気刺激はどこまで運動の代替となるか？応用可能性の検証
公益財団法人 石本記念デサントスポーツ科学振興財団
研究期間 2023年04月 - 運動はヒトの海馬を本当に活性化するのか？
安藤 創一; 田代 学; 藤本 敏彦
日本学術振興会, 科学研究費助成事業, 電気通信大学, 挑戦的研究(萌芽), 運動が脳機能の維持や向上に効果的であることは広く知られている．ヒトを対象とした研究では，運動が脳機能にもたらす効果の検証にはfMRIやNIRSなどのイメージング機器を用いることが一般的である．しかし，メカニズムの解明など侵襲的な手法が必要な場合は動物モデルを用いる必要があり，現在知られている運動と脳に関するエビデンスには，ヒトでは直接検証されていないものが多い．これまでに運動が海馬を活性化させるということが提唱されているが，その根拠となっているものは，動物モデルを用いた研究である．しかし，上述の動物モデルの研究とヒト研究との潜在的な違いを考えると，運動がヒトの海馬を活性化することを直接的に明らかにすることは，科学的エビデンスを正しく伝えるとともに，なぜ一回の運動でもヒトの脳機能の維持・向上につながるのかを示す重要な知見となるものである．そこで本研究では，“運動はヒトの海馬を本当に活性化するのか？”というこれまで直接的に明らかにされていない疑問を解決することを目的とする． 令和3年度は海馬における内因性のドーパミン遊離を定量化することを試みている．薬剤としてドーパミンD2受容体の拮抗薬であり[11C]ラクロプライドを用いたPET実験のデータをもとに解析を行っている．現在，この解析のための方法を検討している段階であり，本研究により，一過性の運動によりドーパミン神経を介して海馬が活性化するかどうかが明らかになることが期待される．, 21K19702
研究期間 2021年07月 - 2023年03月 - 運動中の認知課題遂行における認知・運動・呼吸循環機能の相互関連性
石田 浩司; 片山 敬章; 安藤 創一; 須藤 みず紀; 高石 鉄雄
日本学術振興会, 科学研究費助成事業, 名古屋大学, 基盤研究(C), 運動と認知の二重課題について，一方の課題の種類や難易度を変えた時の，両方のパフォーマンスへの影響と加齢による違い，さらに二重課題開始時の呼吸循環応答の動態を検討した．その結果，1)自転車運動の回転数を変えて二重課題を実施すると，運動の正確性が低下し，高齢者では低速時に速く漕ぐ傾向があること，2)認知課題を変えた時の二重課題では，運動パフォーマンスが作業記憶課題で低下し，認知パフォーマンスでは注意機能が影響を受けやすく，高齢者では向上する場合もあること，3)二重課題開始時の各種応答は単独運動より大きく，それは認知と運動の効果が単純加算されること，高齢者の応答は若年者より遅いことが明らかとなった．, 17K01758
研究期間 2017年04月01日 - 2020年03月31日 - なぜ運動による覚醒レベルの上昇は認知パフォーマンスを高めるのか？
公益財団法人 石本記念デサントスポーツ科学振興財団
研究期間 2019年07月 - エピジェネティック修飾を介する骨格筋糖代謝の分子適応機構の解明
檜垣 靖樹; 田中 宏暁; 須藤 みず紀; 道下 竜馬; 安藤 創一; 上原 吉就; 安野 哲彦
日本学術振興会, 科学研究費助成事業, 福岡大学, 基盤研究(B), 本研究では、骨格筋糖代謝調節機構における重要な分子である、一酸化窒素を合成する酵素(nNOS)の遺伝子発現について、身体不活動、加齢および運動に対する応答にDNAメチル化が関与しているか、検討した。その結果、身体不活動により骨格筋のnNOSのDNAメチル化の増加とタンパク発現の減少を認め、エピジェネティックな遺伝子修飾が関与していることが明らかとなった。また、加齢によりnNOSタンパク発現の亢進を認め、豊かな環境はその亢進を減弱させたが、それらの調節機構にエピジェネティックな遺伝子修飾の関与を証明するには至らなかった。これらの研究成果の一部は、国内外の学術学会及び学術雑誌にて公開した。, 15H03082
研究期間 2015年04月01日 - 2019年03月31日 - 運動が認知機能を高める機序の解明：PETを用いたドーパミンの神経伝達からの検証
安藤 創一; 田代 学; 藤本 敏彦; 檜垣 靖樹
日本学術振興会, 科学研究費助成事業, 電気通信大学, 基盤研究(B), 本研究では，一過性の運動による認知パフォーマンスの向上に脳内でのドーパミンを介した神経伝達が関与するという仮説を検証することを目的とした．被験者は，仰臥位での自転車エルゴメーターによる運動時に認知課題を行い，内因性ドーパミンの遊離を評価した．その結果，運動により認知パフォーマンスの向上と内因性ドーパミンの遊離がみられた．これらの結果は，一過性の運動による認知パフォーマンスの向上に内因性ドーパミンの遊離が関与することを示唆するものである．, 16H03230
研究期間 2016年04月 - 2019年03月 - 骨格筋細胞における核とミトコンドリアの共遊走機構の解明
檜垣 靖樹; 須藤 みず紀; 兼岡 秀俊; 安藤 創一; 安野 哲彦
日本学術振興会, 科学研究費助成事業, 福岡大学, 挑戦的萌芽研究, 肥満者の骨格筋細胞内には多量の脂肪が貯蔵されており、脂肪量とインスリン感受性は負の相関を示す。一方、インスリン感受性が亢進している持久鍛錬者の筋細胞内脂肪量は、肥満者よりもさらに多い。しかし、なぜ持久鍛錬者は多量の筋細胞内脂肪を有するのに、インスリン抵抗性を引き起こさないのか、不明である。 本研究では、iPS細胞由来の筋細胞を用いて、核の周辺にミトコンドリアと脂肪滴が局在することを観察した。我々は、これらの局在環境がインスリン抵抗性と関連していると考えている。, 15K12677
研究期間 2015年04月01日 - 2017年03月31日 - 低酸素環境下での運動中の認知機能：閾値の検討と神経活動の評価法の開発
安藤 創一; 小見山 高明; 片山 敬章; 檜垣 靖樹; 須藤 みず紀
日本学術振興会, 科学研究費助成事業, 電気通信大学, 挑戦的萌芽研究, 本研究の目的は，低酸素環境下での運動が認知機能に与える影響を明らかにすることであった．本研究により，低酸素環境下（吸入気酸素濃度：0.12-0.13）での運動中であっても認知機能が向上することが示された．しかしながら，低酸素環境下での運動中に動脈血酸素飽和度が低下した被験者ほど認知機能の向上がみられなかった．したがって，動脈血酸素飽和度の低下は，低酸素環境下での運動中の認知機能に影響を与える大きな要因であることが明らかとなった．, 15K12664
研究期間 2015年04月 - 2017年03月 - 運動中の認知機能の低下を防ぐ方法と認知機能を改善・向上させるプログラムの開発
安藤 創一
日本学術振興会, 科学研究費助成事業, 若手研究(A), 本研究より得られた主な研究成果は以下の通りである，1) 酸素濃度が15％に低下した低酸素環境下においても，通常環境下と同様に運動により認知機能が向上する，2) 高温環境下での高強度運動中に頸部への冷却を行っても，認知機能には影響を与えない（Ando et al. 2015），3) 朝食を欠食すると認知機能は低下するが，朝食摂取の有無に関係なく運動中に認知機能は向上する（Komiyama et al. 2016）．さらに，これまでの国内外の研究成果を精査し，脳血流の増加および組織酸素飽和度の変化が運動により認知機能を直接的に向上させている要因ではないことを示唆した（Ando 2016）．, 25702039
研究期間 2013年04月 - 2016年03月 - 運動による認知機能の向上は運動様式によって異なるのか？
公益財団法人 石本記念デサントスポーツ科学振興財団
研究期間 2015年07月 - 筋収縮刺激による培養筋細胞を用いたミトコンドリア遊走機構の解明
檜垣 靖樹; 須藤 みず紀; 安藤 創一; 安野 哲彦; 兼岡 秀俊
日本学術振興会, 科学研究費助成事業, 福岡大学, 挑戦的萌芽研究, 肥満者の骨格筋細胞内には多量の脂肪が貯蔵されており、脂肪量とインスリン感受性は負の相関を示す。一方、インスリン感受性が亢進している持久鍛錬者の筋細胞内脂肪量は、肥満者よりもさらに多い。しかし、なぜ持久鍛錬者は多量の筋細胞内脂肪を有するのに、インスリン抵抗性を引き起こさないのか、不明である。 本研究では、培養細胞実験系で、核の周辺にミトコンドリアと脂肪滴が局在すること、また、それらの解剖学的位置関係を有しながら脂肪滴を取り囲む現象を捉えた動画像を得た。インスリン抵抗性の背景に、ミトコンドリアと脂肪滴の解剖学的位置関係が影響する可能性が考えられた。, 25560345
研究期間 2013年04月01日 - 2015年03月31日 - 酸化ストレスは筋トレ-ニング及び筋不活動による骨格筋糖輸送適応を制御する
檜垣 靖樹; 田中 宏暁; 清永 明; 飛奈 卓郎; 須藤 みず紀; 安藤 創一; 山田 陽介
日本学術振興会, 科学研究費助成事業, 福岡大学, 基盤研究(C), 骨格筋線維特性により異なるが、筋細胞には一酸化窒素合成酵素(NOS)の局在を認めることから、酸化ストレスの一つであるNOが、骨格筋の糖輸送の制御を担っているとの仮説を立てた。そこで、我々はトレーニングモデル及び不活動モデルの作成に着手し、上記仮説を検証可能な実験系を立ち上げた。そして、糖輸送の制御にNOSがどのようなメカニズムを持って制御しているか、エピジェネティックな変化を想定して実験を進めた。その結果、NOSプロモータ領域のCpGアイランドのメチル化の定量が可能となり、条件間でメチル化の程度が異なる可能性が示唆された。, 22500618
研究期間 2010年 - 2012年 - 運動中に周辺視野の知覚能力は低下するか?(低酸素環境下での反応時間からの検証)
安藤 創一
日本学術振興会, 科学研究費助成事業, 若手研究(B), 本研究の目的は、一過性の運動が周辺視野での知覚能力に及ぼす影響について検討することであった。通常環境下と低酸素環境下で行われた実験1の結果から、脳の組織酸素飽和度が低下すればするほど周辺視野の知覚能力が低下することが明らかとなった。さらに、実験2から高強度の運動中には周辺視野に注意を向ける能力が低下する可能性が示唆された。これらの結果から、サッカーなどの球技において周りが見えなくなる生理学的要因の解明につながることが期待される。, 21700622
研究期間 2009年 - 2010年 - 運動による生理的・心理的変化が周辺視野で見る能力に及ぼす影響
安藤 創一
日本学術振興会, 科学研究費助成事業, 大阪体育大学, 特別研究員奨励費, 本年度は、安静時および運動中に中心視野と周辺視野に呈示される視覚刺激に対する反応時間を測定した。運動には自転車エルゴメーター(コンビ社製75XL II)を用いた。実験は三日間に分けて行い、実験の初日に最高酸素摂取量を測定し、最高酸素摂取量の65%に相当する運動負荷を決定した。実験二日目および三日目には、中心視野と周辺視野のそれぞれに呈示される視覚刺激に対する反応時間を、安静時、運動中の順で測定した。視覚刺激の作成及び呈示にはプログラム言語MATLAB(Mathwork社)を用いた。中心視野と周辺視野の反応時間は異なる日に測定し、半数の実験参加者は中心視野→周辺視野の順で、残りの半数の参加者は周辺視野→中心視野の順で行った。安静時および自転車運動中には、反応時間と併せて心拍数(HR)、主観的運動強度(RPE)を測定した。その結果、運動中の周辺視野反応時間は安静時と比較して有意に大きい値を示した。一方、運動中の中心視野反応時間は安静時と差がみられなかった。HR&RPEはそれぞれの測定日の間で差がみられなかった。以上の結果から、周辺視野に呈示される視覚刺激に対して反応する能力が、中心視野に呈示される視覚刺激に対して反応する能力と比較して一過性の運動の影響を受けやすいことが示唆された。以上の結果は国際バイオメカニクス学会にて発表を行った後、国際雑誌に受理された(Ando, et. al. in press)。, 05J06459
研究期間 2005年 - 2007年
